Prevalence of urinary tract infection and risk factors among Saudi patients with diabetes

Prevalence of urinary tract infection and risk factors among Saudi patients with diabetes
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DOI:
10.1007/s00345-012-0934-x
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发表时间:
2013-06-01
影响因子:
3.4
通讯作者:
Rafiullah, M. R. M.
Rafiullah, M. R. M.
中科院分区:
医学2区
文献类型:
--
作者:
Al-Rubeaan, Khalid A.;Moharram, Osama;Rafiullah, M. R. M.

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本研究的目的是评估沙特糖尿病患者尿路感染(UTI)的患病率及其危险因素。共纳入1000名糖尿病患者。每6个月对患者进行一次访问和检查。尿路感染的患病率为25.3%,男性和女性分别为7.2%和41.1%。女性患UTI的风险最高(RR = 6.102; CI = 4.343-8.573; P < 0.001)。年龄、糖尿病病程、HbA1c对UTI的发生无影响,而BMI大于30 kg/m(2)会增加UTI的发生风险(RR = 1.722; CI = 1.532 ~ 1.935; P < 0.001)。1型和2型糖尿病患者尿路感染的发生率相似(23.7%和25.6%)。60岁以上患者无显著风险(RR = 1.054; CI = 0.841 ~ 1.321; P = 0.651)。与尿路感染相关的危险因素有高血压(RR = 1.202; CI = 1.061 ~ 1.361; P = 0.006)、胰岛素治疗(RR = 1.411; CI = 1.262 ~ 1.578; P < 0.001)和肾病(微量白蛋白尿)(RR = 1.417; CI = 1.036 ~ 1.939; P = 0.031)。目前的研究表明,尿路感染在女性糖尿病患者和BMI大于30 kg/m的糖尿病患者中患病率更高(2)。与普通糖尿病人群尿路感染相关的其他危险因素有微量蛋白尿、高血压和胰岛素治疗。
The aim of this study is to assess the prevalence of urinary tract infection (UTI) and its risk factors among Saudi diabetics.A total of 1,000 diabetic patients were included. Patients were interviewed and examined at each visit every 6 months.The prevalence of UTI was 25.3 % in total diabetic population and 7.2 and 41.1 % in males and females, respectively. Females have highest risk of UTI (RR = 6.102; CI = 4.343-8.573; P < 0.001). Age, duration of diabetes and HbA1c did not influence the incidence of UTI, while BMI above 30 kg/m(2) increased the risk (RR = 1.722; CI = 1.532-1.935; P < 0.001). The incidence of UTI in both type 1 and 2 diabetics was similar (23.7 and 25.6 %). There was no significant risk in patients aged above 60 years (RR = 1.054; CI = 0.841-1.321; P = 0.651). The risk factors found to be associated with UTI were hypertension (RR = 1.202; CI = 1.061-1.361; P = 0.006), insulin therapy (RR = 1.411; CI = 1.262-1.578; P < 0.001) and nephropathy (microalbuminuria) (RR = 1.417; CI = 1.036-1.939; P = 0.031).The present study has shown that prevalence of UTI is more in diabetic females and diabetics with BMI above 30 kg/m(2). The other risk factors associated with UTI in general diabetic population were found to be microalbumniuria, hypertension and insulin therapy.