Insulin resistance influences weight loss in non-obese women who followed a home-based exercise program and slight caloric restriction.

Insulin resistance influences weight loss in non-obese women who followed a home-based exercise program and slight caloric restriction.
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DOI:
10.1016/j.diabres.2011.02.031
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发表时间:
2011-06
影响因子:
5.1
通讯作者:
Sichieri, Rosely
Sichieri, Rosely
中科院分区:
医学3区
文献类型:
--
作者:
Felix Mediano, Mauro Felippe;Sichieri, Rosely

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This study aimed to evaluate the influence of insulin resistance status on weight changes in non-obese women who followed a home-based exercise program and slight caloric restriction over a period of 12 months. Middle-aged (25–45 yr), non-obese (body mass index of 23–29.9 kg/m2) women were randomly assigned to control (CG) or home-based exercise group (HB). The HB group received a booklet explaining the physical exercises to be practiced at home at least three times per week (40 min/session). Both groups were required to follow a small energy restriction of 100–300 calories per day. For the analysis, women were stratified in two groups according to baseline insulin sensitivity: NIR (non-insulin resistant; n=121) and IR (insulin resistant; n=64). Women classified as IR at baseline had greater weight loss after 12 months of follow-up (−1.6 kg vs. −1.1 kg; p=0.01), and HB exercise helped to reduce weight only among NIR women (−1.5 vs. −0.7; p=0.04); no differences were observed between intervention groups for IR women (−1.5 vs. −1.7; p=0.24). There were no differences between IR and NIR groups for lipid profile after adjustment for weight changes. Insulin resistance facilitated weight loss, and home-based exercise promoted greater weight loss only in non-insulin resistance women.
DOI: 10.1590/s0004-27302007000600015
发表时间: 2007-08-01
期刊: Arquivos Brasileiros de Endocrinologia & Metabologia
影响因子: --
作者:
Mediano, Mauro Felippe Felix;Barbosa, José Silvio de Oliveira;Pereira, Rosângela Alves
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影响因子: 16.2
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发表时间: 2010-03-01
影响因子: 5.9
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影响因子: 2.1
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