ROLE OF THORACOTOMY IN THE MANAGEMENT OF PULMONARY METASTASES FROM MALIGNANT-MELANOMA
ROLE OF THORACOTOMY IN THE MANAGEMENT OF PULMONARY METASTASES FROM MALIGNANT-MELANOMA
复制标题
DOI：
10.1016/s0003-4975(10)63302-4
复制
发表时间：
1979-01-01
影响因子：
4.6
通讯作者：
PEABODY, J
中科院分区：
文献类型：
--
作者：
MATHISEN, DJ;FLYE, MW;PEABODY, J
在21年的时间里，33名患者接受了开胸手术切除疑似恶性黑色素瘤肺转移瘤。11名患者被发现患有非恶性疾病（第1组）; 10名患者被发现患有不可切除的疾病（第2组）; 12名患者无病（第3组）。在发现患有黑色素瘤的患者中，22人中有20人接受了术后化疗。第2组患者的中位生存期为10.5个月（3至20个月）;第3组为12个月（3至35个月）。没有5年的幸存者。术前无因素区分三组。根据文献中黑色素瘤肺转移瘤切除术后存活超过5年的患者报告，手术切除仍然提供了最大的长期生存机会。开胸术对于那些没有发现转移性疾病的患者的分期特别有用。
Thirty-three patients over a 21-year period underwent thoracotomy for resection of suspected pulmonary metastases from malignant melanoma. Eleven patients were found to have nonmalignant disease (Group 1); 10 were found to have unresectable disease (Group 2); and 12 were rendered disease-free (Group 3). Of the patients found to have melanoma, 20 of 22 received postoperative chemotherapy. The median survival of the patients in Group 2 was 10.5 months (3 to 20 months); in Group 3 it was 12 months (3 to 35 months). There were no 5-year survivors. No factors distinguished the three groups preoperatively. Surgical resection still offers the greatest chance for long-term survival, based on reports of patients in the literature who have survived longer than 5 years following resection of pulmonary metastases from melanoma. Thoracotomy is especially useful for staging purposes in those patients found to have no metastatic disease.