Untargeted mass spectrometry-based metabolomics approach unveils molecular changes in raw and processed foods and beverages
Untargeted mass spectrometry-based metabolomics approach unveils molecular changes in raw and processed foods and beverages
复制标题
DOI：
10.1016/j.foodchem.2019.125290
复制
发表时间：
2020-01-01
期刊：
影响因子：
8.8
通讯作者：
Dorrestein, Pieter C.
中科院分区：
文献类型：
--
作者：
Gauglitz, Julia M.;Aceves, Christine M.;Dorrestein, Pieter C.
在我们的日常生活中，我们食用的食物是由我们自己或他人运输、储存、准备、烹饪或以其他方式加工的。食品的储存和制备对食品的化学成分有着巨大的影响。食品样品的非靶向质谱分析有可能通过检测广谱化学物质来增加我们对这些过程的化学理解。我们使用非靶向质谱和分子网络对食品在常见制备过程中的化学变化进行了基于时间的分析，例如发酵，酿造和成熟。提出的数据分析工作流程实现了一种研究食品化学变化的方法，可以揭示化学特征的全球变化，确定丰度的变化，以及确定特定的化学物质及其转化产物。本研究生成的数据是公开的，可以单独复制和重新分析这些数据，并作为未来调查的基线数据集。
In our daily lives, we consume foods that have been transported, stored, prepared, cooked, or otherwise processed by ourselves or others. Food storage and preparation have drastic effects on the chemical composition of foods. Untargeted mass spectrometry analysis of food samples has the potential to increase our chemical understanding of these processes by detecting a broad spectrum of chemicals. We performed a time-based analysis of the chemical changes in foods during common preparations, such as fermentation, brewing, and ripening, using untargeted mass spectrometry and molecular networking. The data analysis workflow presented implements an approach to study changes in food chemistry that can reveal global alterations in chemical profiles, identify changes in abundance, as well as identify specific chemicals and their transformation products. The data generated in this study are publicly available, enabling the replication and re-analysis of these data in isolation, and serve as a baseline dataset for future investigations.