Impact of comorbid anxiety in an effectiveness study of interpersonal psychotherapy for depressed adolescents.
Impact of comorbid anxiety in an effectiveness study of interpersonal psychotherapy for depressed adolescents.
复制标题
共病焦虑对抑郁青少年人际心理治疗有效性研究的影响。
DOI：
10.1097/01.chi.0000222791.23927.5f
复制
发表时间：
2006
影响因子：
13.3
通讯作者：
Davies,Mark
中科院分区：
文献类型：
--
作者：
Young,JamiF;Mufson,Laura;Davies,Mark
目的通过青少年抑郁人际心理治疗（IPT-A）的有效性研究，评估共病焦虑对青少年抑郁治疗的影响。方法：1999年4月1日至2002年7月31日进行随机临床试验。63名年龄在12至18岁之间的抑郁青少年接受了IPT-A治疗或由学校心理健康临床医生提供的常规治疗。有和没有可能的共病焦虑症的青少年在抑郁和整体功能上进行比较。所有分析均采用意向治疗设计。结果共病焦虑与基线时较高的抑郁评分（p < 0.01）和治疗后较差的抑郁结局相关（p < 0.05）。IPT-A治疗青少年伴发焦虑的抑郁效果无显著性差异（p = 0.07）。在治疗过程中抑郁和功能改善的青少年在焦虑方面也有改善（p < 0.01），与治疗条件无关。结论青少年抑郁、焦虑共病患者抑郁程度加重，治疗难度加大。与支持性治疗相比，像IPT-A这样的结构化治疗可能对共病抑郁症青少年特别有帮助。j。儿童与青少年精神病学,2006;45(8):904 - 912。
OBJECTIVETo assess the impact of comorbid anxiety on treatment for adolescent depression in an effectiveness study of interpersonal psychotherapy for depressed adolescents (IPT-A).METHODA randomized clinical trial was conducted from April 1, 1999, through July 31, 2002. Sixty-three depressed adolescents, ages 12 to 18, received either IPT-A or treatment as usual delivered by school-based mental health clinicians. Adolescents with and without probable comorbid anxiety disorders were compared on depression and overall functioning. All analyses used an intent-to-treat design.RESULTSComorbid anxiety was associated with higher depression scores at baseline (p <.01) and poorer depression outcome posttreatment (p <.05). IPT-A was nonsignificantly more effective in treating the depression of adolescents with comorbid anxiety (p =.07). Adolescents whose depression and functioning improved during the course of treatment also showed an improvement in anxiety (p <.01), largely irrespective of treatment condition.CONCLUSIONSAdolescents with comorbid depression and anxiety present with more severe depression and may be more difficult to treat. Structured treatments like IPT-A may be particularly helpful for comorbidly depressed adolescents as compared to supportive therapy. J. Am. Acad. Child Adolesc. Psychiatry, 2006;45(8):904-912.