Eye disorders in patients with multiple sclerosis: natural history and management.
Eye disorders in patients with multiple sclerosis: natural history and management.
复制标题
DOI：
10.2147/opth.s6383
复制
发表时间：
2010-12-06
期刊：
影响因子：
--
通讯作者：
Balcer LJ
中科院分区：
文献类型：
--
作者：
Graves J;Balcer LJ
多发性硬化症（MS）是一种中枢神经系统脱髓鞘疾病，是年轻人残疾的主要原因。视力障碍是该患者人群残疾的常见组成部分。视神经、脑干和小脑的损伤导致影响传入和传出视觉通路的特征性综合征。本综述的目的是总结多发性硬化症患者的眼部疾病谱，他们的自然病史，以及目前的诊断和管理策略。我们强调最常见的疾病，包括视神经炎和核间性眼麻痹，并包括新的技术，如光学相干断层扫描，这将使我们更好地了解MS及其对视觉系统的影响。
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system and leading cause of disability in young adults. Vision impairment is a common component of disability for this population of patients. Injury to the optic nerve, brainstem, and cerebellum leads to characteristic syndromes affecting both the afferent and efferent visual pathways. The objective of this review is to summarize the spectrum of eye disorders in patients with MS, their natural history, and current strategies for diagnosis and management. We emphasize the most common disorders including optic neuritis and internuclear ophthalmoparesis and include new techniques, such as optical coherence tomography, which promise to better our understanding of MS and its effects on the visual system.