Forensic analysis of inks by imaging desorption electrospray ionization (DESI) mass spectrometry
Forensic analysis of inks by imaging desorption electrospray ionization (DESI) mass spectrometry
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DOI：
10.1039/b700236j
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发表时间：
2007-01-01
期刊：
影响因子：
4.2
通讯作者：
Cooks, R. G.
中科院分区：
文献类型：
--
作者：
Ifa, D. R.;Gumaelius, L. M.;Cooks, R. G.
解吸电喷雾电离质谱法（DES-MS）用于文件的法医分析。普通书写纸上的蓝色圆珠笔油墨在环境条件下进行检测，无需事先进行样品制备。当耦合到自动移动平台时，生成二维分子图像。原理证明实验包括模拟伪造数字的特征描述和旧的书面记录的检查。DESI的这种应用在速度和样品保存方面优于提取技术。的解吸溶剂组合物，在这种情况下，甲醇和水的混合物，和流速的影响，进行评估。结果表明，分析物（染料碱性蓝7，碱性紫3和溶剂蓝26）的溶解度起着重要的作用，从纸表面的解吸。
Desorption electrospray ionization mass spectrometry (DESI-MS) is employed in the forensic analysis of documents. Blue ballpoint pen inks applied to ordinary writing paper are examined under ambient conditions without any prior sample preparation. When coupled to an automated moving stage, two-dimensional molecular images are generated. Proof-of-principle experiments include characterization of a simulated forged number and examination of older written records. This application of DESI has advantages over extractive techniques in terms of speed and sample preservation. The effects of the desorbing solvent composition, in this case a mixture of methanol and water, and of flow rate, are evaluated. Results suggest that the solubility of the analyte ( dyes Basic Blue 7, Basic Violet 3 and Solvent Blue 26) plays an important role in desorption from the paper surface.