Relationship between visual acuity and visual field and its reproducibility in patients with retinitis pigmentosa
Relationship between visual acuity and visual field and its reproducibility in patients with retinitis pigmentosa
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DOI：
10.1038/s41433-022-02043-0
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发表时间：
2022-04-20
期刊：
影响因子：
3.9
通讯作者：
Inoue，Tatsuya
中科院分区：
文献类型：
--
作者：
Asaoka，Ryo;Miyata，Manabu;Inoue，Tatsuya
目的探讨视网膜色素变性(RP)患者视力(VA)与视野(VF)的关系及其可重复性。在3个月的时间内进行两次Humphrey VF测试(10-2瑞典交互阈值算法[SITA]测试)，使用每个VF测试点灵敏度的均方根误差(RMSE)来计算重复性。研究了最小分辨角(LogMAR)的对数与VF灵敏度之间的关系。分析RMSE与年龄、注视丧失、假阳性、假阴性和对数视力的关系。结果视觉敏感度与视力的相关性在中心凹最为密切，向周边偏心减弱。VF的重复性随着VA的降低而显著增加。与对数MAR VA ≤ 0时相比，当对数MAR VA为0.5时，重复性显著降低。结论VF试验的重复性随VA的降低而降低。当患者的对数视力为0.5时，仔细考虑是必要的。
Background/ObjectivesTo investigate the association between visual acuity (VA) and visual field (VF) and its reproducibility in patients with retinitis pigmentosa (RP).Subjects/MethodsThe study cohort comprised 227 eyes of 227 patients with RP. The reproducibility of two Humphrey VF tests (10-2 Swedish Interactive Threshold Algorithm [SITA] tests) performed within a period of 3 months was calculated using the root mean squared error (RMSE) of each VF test point’s sensitivity. The association between the logarithm of the minimum angle of resolution (logMAR) VA and VF sensitivity was investigated. Additionally, the relationship between RMSE and age, fixation loss, false positives, false negatives, and logMAR VA was determined.ResultsThe association between visual sensitivity and VA was most tight at the fovea, and it became weak toward the peripheral region in an eccentric manner. VF reproducibility appreciably increased as VA decreased. In particular, reproducibility was significantly decreased when logMAR VA was >0.5 compared with logMAR VA ≤ 0.ConclusionReproducibility of VF tests decreases with a decrease in VA. Careful consideration is necessary when a patient’s logMAR VA is >0.5.