Degeneration and Regeneration of Taste Buds
Degeneration and Regeneration of Taste Buds
复制标题
味蕾的退化与再生
DOI：
10.1007/978-3-642-65245-5_4
复制
发表时间：
1971
影响因子：
3.2
通讯作者：
L. Guth
中科院分区：
文献类型：
--
作者：
L. Guth
在哺乳动物和鱼类中，味蕾的维持需要完整的神经支配。Vintschgau和Honigschmied（1876）发现，切断家兔的舌咽神经会导致同侧腭状乳头的味蕾消失。随后在犬中证实，舌神经（Olmsted，1921）或鼓索神经（Olmsted，1922）横断后，舌前部的味蕾退化，但翼管神经横断或三叉神经节摘除后则不退化（Wirtanen和Olmsted，1934）。在鱼类中，味蕾的完整性同样依赖于完整的神经支配（Olmsted，1920 a），但两栖动物的关系不太清楚。在有尾目动物（蝾螈或蝾螈）中还没有进行类似的去神经研究，而无尾目动物（青蛙）的味觉器官形态与鱼类、有尾目动物或哺乳动物的味觉器官形态完全不同，这一点将在后面讨论。
In the mammal and fish, an intact innervation is required for the maintenance of taste buds. Vintschgau and Honigschmied (1876) showed that transection of the glossopharyngeal nerve in rabbits resulted in a disappearance of taste buds from the ipsilateral vallate papillae. It was subsequently demonstrated in dogs that taste buds on the anterior portion of the tongue degenerate after lingual (Olmsted, 1921) or chorda tympani (Olmsted, 1922) nerve transection, but not after vidian nerve transection or trigeminal ganglion extirpation (Wirtanen and Olmsted, 1934). In fish, the integrity of the taste bud is likewise dependent on an intact innervation (Olmsted, 1920a), but the relationship is less clearly understood for the amphibia. Comparable denervation studies have not been performed in urodeles (salamander or newt) and the morphology of the taste organ in anurans (frog) is, as will be discussed later, quite distinct from that of fish, urodele, or mammal.