Prostaglandins and leukotrienes in pulmonary O2 toxicity.
Prostaglandins and leukotrienes in pulmonary O2 toxicity.
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前列腺素和白三烯在肺氧中毒中的作用。
DOI：
10.1007/978-1-4684-5568-7_161
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Patton,LM
中科院分区：
文献类型：
--
作者：
Faiman,MD;Patton,LM
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Lawrence, Kansas 66045, USA02 radicals can initiate peroxidation of cellular membranes, resulting in the release of hydrolytic enzymes, decreased membrane fluidity, and compromised membrane integrity. Free radicals also may cause the release of vasoactive substances, including prostaglandins (PG) and 1eukotrienes (LT). These products of the arachidonic acid cascade have been shown to produce vasoconstriction, vasodilation, platelet aggregation, increased capillary permeability, plasma extravasation, and edema formation. Of interest is that a similar pathophysiology is seen after 02 exposure. Employing the isolated perfused lung (IPL) prepared from lungs of rats exposed to 100% 02, the role of PG and LT in 02-induced lung damage was studied.
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白三烯抑制剂可减轻过氧化氢引起的大鼠肺损伤。
DOI：
10.1164/arrd.1985.131.5.778
发表时间：
1985
期刊：
The American review of respiratory disease
影响因子：
--
作者：
Burghuber,OC;Strife,RJ;Zirrolli,J;Henson,PM;Henson,JE;Mathias,MM;Reeves,JT;Murphy,RC;Voelkel,NF
通讯作者：
Voelkel,NF
前列腺素 E 1 和 F 1 α 平滑肌生物测定的评估。
影响因子：
3.3
作者：
J. Weeks;J. R. Schultz;W. E. Brown
通讯作者：
W. E. Brown
4-(1H-四唑-5-基)-1H-吲哚。
DOI：
10.1107/s1600536810033271
发表时间：
2010
期刊：
Acta crystallographica. Section E, Structure reports online
影响因子：
--
作者：
Ge,Yu-Hua;Han,Pei;Wei,Ping;Ou-Yang,Ping-Kai
通讯作者：
Ou-Yang,Ping-Kai
体内高氧暴露对大鼠离体灌注肺释放内源性组胺的影响。
影响因子：
3.8
作者：
Januszkiewicz,AJ;Faiman,MD
通讯作者：
Faiman,MD