Dynamics of Hepatitis B Virus Infection: What Causes Viral Clearance?

Dynamics of Hepatitis B Virus Infection: What Causes Viral Clearance?
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DOI:
10.1080/08898480.2011.564563
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发表时间:
2011-01-01
影响因子:
1.8
通讯作者:
Schaeffer, David G.
Schaeffer, David G.
中科院分区:
法学3区
文献类型:
--
作者:
Ciupe, Stanca M.;Catlla, Anne J.;Schaeffer, David G.

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乙型肝炎病毒感染肝细胞,导致急性或慢性肝病。免疫反应包括治疗和杀死细胞。稳定性分析表明,病毒清除仅取决于杀伤和固化结合的强度,而与固化细胞的特性无关。
The virus Hepatitis B infects liver cells, leading to either acute or chronic liver disease. Immune responses involve both curing and killing of cells. Stability analyses show that viral clearance depends only on the strength of the combined killing and curing, independent of the characteristics of the cured cells.