Molecular cloning, functional expression and chromosomal localization of a human homolog of the cyclic nucleotide-gated ion channel of retinal cone photoreceptors.
Molecular cloning, functional expression and chromosomal localization of a human homolog of the cyclic nucleotide-gated ion channel of retinal cone photoreceptors.
复制标题
视网膜锥光感受器环核苷酸门控离子通道的人类同源物的分子克隆、功能表达和染色体定位。
DOI：
10.1016/0014-5793(96)00889-7
复制
发表时间：
1996
期刊：
影响因子：
3.5
通讯作者：
Yau,KW
中科院分区：
文献类型：
--
作者：
Yu,WP;Grunwald,ME;Yau,KW
We have cloned from human retina a cyclic nucleotide‐gated (CNG) ion channel that is distinct from the one found in rod photoreceptors. This channel protein is highly homologous to the CNG channel that recently has been cloned from bovine testis and kidney and has been shown to be present i retinal cone photoreceptors. When expressed in human embryonic kidney cells, the protein forms functional ion channels with properties broadly similar to those described for the cloned bovine channel. The gene for this channel resides on chromosome 2.
