A nucleotide diphosphate kinase mediates tethering between mitochondria prior to fusion.
A nucleotide diphosphate kinase mediates tethering between mitochondria prior to fusion.
复制标题
核苷酸二磷酸激酶在融合前介导线粒体之间的束缚。
DOI：
10.1083/jcb.202309037
复制
发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Sesaki,Hiromi
中科院分区：
文献类型：
--
作者：
Ikeda,Arisa;Iijima,Miho;Sesaki,Hiromi
线粒体融合在它们的结构和功能中起着重要作用。在这个问题上，苏等人（2023. 202301091）报道了核苷二磷酸激酶NME 3在融合之前通过其直接膜结合和六聚化而不是其激酶活性促进线粒体拴系。
Mitochondrial fusion plays an important role in both their structure and function. In this issue, Su et al. (2023. J. Cell Biol. https://doi.org/10.1083/jcb.202301091) report that a nucleoside diphosphate kinase, NME3, facilitates mitochondrial tethering prior to fusion through its direct membrane-binding and hexamerization but not its kinase activity.