Multilevel Manipulation of Supramolecular Structures of Giant Molecules via Macromolecular Composition and Sequence.
Multilevel Manipulation of Supramolecular Structures of Giant Molecules via Macromolecular Composition and Sequence.
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DOI：
10.1021/acsmacrolett.8b00275
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发表时间：
2018-05
影响因子：
5.8
通讯作者：
Wei Zhang;Shuailin Zhang;Qingyun Guo;Xinlin Lu;Yuchu Liu;J. Mao;C. Wesdemiotis;Tao Li;Yiwen Li;Stephen Z. D. Cheng
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文献类型：
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作者：
Wei Zhang;Shuailin Zhang;Qingyun Guo;Xinlin Lu;Yuchu Liu;J. Mao;C. Wesdemiotis;Tao Li;Yiwen Li;Stephen Z. D. Cheng
基于多面体低聚倍半硅氧烷（POSS）纳米粒子，采用正交“点击”策略成功合成了一系列单分散链状大分子，其组成和序列均得到精确控制。它们的非球形超分子结构，如层状，双螺旋，和六方填充的圆柱体，主要是由组成（即，纳入两亲性纳米粒子的数量）。此外，通过精确地改变具有相同化学组成的巨分子中纳米颗粒的排列顺序，可以微调其超分子结构的畴大小。这是由于大分子构象的差异所造成的集体氢键相互作用在每一组序列异构的巨分子。这项工作已经证明了多层次操纵的超分子结构的巨分子：粗调谐的组成和微调的序列。
We have successfully synthesized a series of monodispersed chain-like giant molecules with precisely controlled macromolecular composition and sequence based on polyhedral oligomeric silsesquioxane (POSS) nanoparticles using an orthogonal "click" strategy. Their nonspherical supramolecular structures, such as lamellae, double gyroids, and hexagonal packed cylinders, are mainly determined by the composition (namely, the number of incorporated amphiphilic nanoparticles). In addition, by precisely alternating the sequence of arranged nanoparticles in the giant molecules with identical chemical compositions, the domain sizes of their supramolecular structures could be fine-tuned. This is attributed to the macromolecular conformational differences caused by collective hydrogen bonding interactions in each set of sequence isomeric giant molecules. This work has demonstrated multilevel manipulation of supramolecular structures of giant molecules: coarse tuning by composition and fine-tuning by sequence.