Reduced blood flow increases the in vivo ammonium ion concentration in the RIF-1 tumor.
Reduced blood flow increases the in vivo ammonium ion concentration in the RIF-1 tumor.
复制标题
血流量减少会增加 RIF-1 肿瘤中的体内铵离子浓度。
DOI：
10.1016/0360-3016(94)00658-8
复制
发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Gamcsik,MP
中科院分区：
文献类型：
--
作者：
Constantinidis,I;Gamcsik,MP
PurposePrevious studies from our laboratory have suggested that pooling of ammonium in tumor tissues may be caused by its inefficient removal due to the poor vasculature commonly found in tumors. The purpose of these experiments was to validate the relationship between tumor ammonium ion concentration and tumor blood flow, and to determine whether large concentrations of ammonium ion detected by Nuclear Magnetic Resonance (NMR) spectroscopy are either produced within the tumor or simply imported into the tumor through the blood stream.
