Body surface area as a predictor of aortic and pulmonary valve diameter
Body surface area as a predictor of aortic and pulmonary valve diameter
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DOI：
10.1016/s0022-5223(00)70092-4
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发表时间：
2000-05-01
影响因子：
6
通讯作者：
Fronk, DM
中科院分区：
文献类型：
--
作者：
Capps, SB;Elkins, RC;Fronk, DM
背景资料：从非心脏解剖测量预测心脏瓣膜尺寸将有利于儿科心脏病专家，成人心脏病专家和心脏外科医生在许多决策情况。以往的研究中，瓣膜大小与身体大小的相关性是通过使用固定的尸检标本、血管造影和超声心动图来实现的，但主要是在年轻人中，本研究探讨体表面积与左心室-主动脉交界处测量的关系（主动脉瓣环直径）和右心室-肺动脉干交界处方法：对1985年6月至1998年10月间6801例心脏瓣膜进行形态学分析。供体年龄为新生儿至59岁（平均31 +/- 17岁;中位数32岁）。计算的体表面积范围为0.18至3.55 m（2）。从适合同种异体移植的摘除瓣膜测量主动脉瓣（n = 4636）和肺动脉瓣（n = 5480）直径。结果：成年男性（年龄大于或等于17岁）的平均主动脉瓣直径为23.1 ± 2.0 mm（n = 2214），平均肺动脉瓣直径为26.2 ± 2.3 mm（n = 2589）。对于成年女性，平均主动脉瓣直径为21.0 ± 1.8 mm（n = 1156），平均肺动脉瓣直径为23.9 ± 2.2 mm（n = 1408），平均主动脉瓣面积指数为2.02 ± 0.52 cm（2）/m2，肺动脉瓣面积指数为2.65 ± 0.52 cm（2）/m2。82%至85%的变异性可由患者的体型解释。结论：主动脉瓣和肺动脉瓣直径与体型密切相关，体表面积与其他临床常用的测量指标结合使用，可作为评估正常主动脉瓣和肺动脉瓣大小的有效工具。
Background: Predicting cardiac valve size from noncardiac anatomic measurements would benefit pediatric cardiologists, adult cardiologists, and cardiac surgeons in a number of decision-making situations. Previous studies correlating valve size with body size have been generated with the use of fixed autopsy specimens, angiography, and echocardiography, but primarily in the young, This study examines the relation of body surface area to measurements of the left ventricular-aortic junction (aortic valve anulus diameter) and the right ventricular-pulmonary trunk junction (pulmonary valve anulus diameter) in 6801 hearts across a wide spectrum of ages.Methods: From June 1985 to October 1998, cardiac valves from 6801 donated hearts were analyzed morphologically. Donor age was newborn to 59 years (mean 31 +/- 17 years; median 32 years). Calculated body surface areas ranged from 0.18 to 3.55 m(2). Aortic (n = 4636) and pulmonary valve diameters (n = 5480) were measured from enucleated valves suitable for allograft transplantation. Mean valve sizes were computed for ranges in body surface area in 0.1-m(2) increments.Results: For adult men (age greater than or equal to 17 years), the mean aortic valve diameter was 23.1 +/- 2.0 mm (n = 2214) and the mean pulmonary valve diameter was 26.2 +/- 2.3 mm (n = 2589). For adult women, the mean aortic valve diameter was 21.0 +/- 1.8 mm (n = 1156) and the mean pulmonary valve diameter was 23.9 +/- 2.2 mm (n = 1408), The mean indexed aortic valve area was 2.02 +/- 0.52 cm(2)/m(2) and the pulmonary valve area 2.65 +/- 0.52 cm(2)/m(2). Between 82% and 85% of the variability was explained by the size of the patient. Regression equations were developed both overall and separately for men and women, although the additional contribution of sex above that of body size was less than 1%.Conclusions: Aortic and pulmonary valve diameters are closely related to body size, Thus, body surface area, when used in conjunction with other clinically accepted evaluations, is a useful tool for estimating normal aortic and pulmonary valve size.