A clinical report of thymoleptic-responsive atypical paranoid psychoses.
A clinical report of thymoleptic-responsive atypical paranoid psychoses.
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胸闷反应性非典型偏执型精神病的临床报告。
DOI：
10.1176/ajp.140.9.1187
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Barreira,PJ
中科院分区：
文献类型：
--
作者：
Akiskal,HS;Arana,GW;Baldessarini,RJ;Barreira,PJ
五名患者的偏执障碍缓解后，治疗胸腺药物，尽管没有充分的情感综合征。他们入院时的临床症状包括多疑、高度警惕、参照系、敌意、好战、受迫害或不忠妄想。部分患者有躯体主诉或明显的恐惧焦虑症状，有情感性障碍家族史，或既往有抗胸腺药物反应。这些观察结果表明，一些没有完整的DSM-III情感综合征的偏执型精神病患者可能只对抗抑郁药物治疗有反应，即不使用抗精神病药物。对这一现象进行系统的前瞻性研究将有助于确定此类患者的诊断标准和治疗反应的范围。
The paranoid disorders of five patients remitted after treatment with thymoleptic agents despite the absence of a full affective syndrome. Their clinical symptoms at admission included suspiciousness, hypervigilance, ideas of reference, hostility, belligerence, and delusions of persecution or of infidelity. Some had phasic disturbances with somatic complaints or prominent phobic anxiety symptoms, a family history of affective disorder, or prior responses to thymoleptic drugs. These observations suggest that some patients with paranoid psychosis who do not have a full DSM-III affective syndrome may respond to antidepressant pharmacotherapy alone, ie, without neuroleptics. Systematic, prospective studies of this phenomenon would help to ascertain diagnostic criteria for such patients and the range of therapeutic responses.