Duration of anal human papillomavirus infection among immunocompetent women: clues to anal cancer epidemiology and possible prevention strategies.

Duration of anal human papillomavirus infection among immunocompetent women: clues to anal cancer epidemiology and possible prevention strategies.
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免疫功能正常的女性中肛门人乳头瘤病毒感染的持续时间:肛门癌流行病学的线索和可能的预防策略。

DOI:
10.1086/596759
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发表时间:
2009
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
--
通讯作者:
Chiao,ElizabethY
Chiao,ElizabethY
中科院分区:
--
文献类型:
--
作者:
Chiao,ElizabethY

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Squamous cell cancer of the anus (SCCA) is a rare malignancy in the general US population; however, the incidence of SCCA has increased significantly in the past decade among both men and women, especially among individuals aged 35–54 years [1]. SCCA, like invasive squamous cell cancer of the cervix, has been etiologically linked to human papillomavirus (HPV) infection; thus, the increased incidence of anal cancer likely reflects the changing epidemiology of HPV infection [2].Although the increased incidence of SCCA among the growing population of immunosuppressed individuals in the United States accounts for some of the overall increased incidence [3], immunocompetent women with cervical disease [4, 5] and men who have sex with men [6] are also at an elevated risk for SCCA. Although several studies have evaluated
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