Neural Correlates of Associative Face Memory in the Anterior Inferior Temporal Cortex of Monkeys
Neural Correlates of Associative Face Memory in the Anterior Inferior Temporal Cortex of Monkeys
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DOI：
10.1523/jneurosci.0471-10.2010
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发表时间：
2010-11-10
影响因子：
5.3
通讯作者：
Tamura, Ryoi
中科院分区：
文献类型：
--
作者：
Eifuku, Satoshi;Nakata, Ryuzaburo;Tamura, Ryoi
为了研究面部识别的联想方面的神经基础，我们记录了猕猴腹侧前下颞叶皮层（AITv）的神经元活动，在执行非对称配对联想（阿帕）任务时，需要一个抽象的模式和一个人的五个不同的面部视图之间的联想配对。在阿帕任务中，一对元素（抽象图案或面孔）作为样本线索呈现后，寻求奖励的猴子在各种重复呈现的测试刺激（面孔或图案）中正确识别出另一个元素。结果显示，大量AITv神经元对面孔和抽象图案都有反应，并且其中大多数神经元选择性地对特定的联想对做出反应。结果表明，除了阿帕任务中使用的面孔的视图不变身份外，AITv神经元群体还能够表示面孔和抽象模式之间的关联配对，这是通过阿帕任务中的训练获得的。此外，联想配对的效果似乎还没有那么强，以至于抽象图案可以用类似于属于一个独特身份的一系列面孔的方式来处理。总之，这些发现表明，AITv在面部识别和面部身份的语义关联中起着至关重要的作用。
To investigate the neural basis of the associative aspects of facial identification, we recorded neuronal activity from the ventral, anterior inferior temporal cortex (AITv) of macaque monkeys during the performance of an asymmetrical paired-association (APA) task that required associative pairing between an abstract pattern and five different facial views of a single person. In the APA task, after one element of a pair (either an abstract pattern or a face) was presented as a sample cue, the reward-seeking monkey correctly identified the other element of the pair among various repeatedly presented test stimuli (faces or patterns) that were temporally separated by interstimulus delays. The results revealed that a substantial number of AITv neurons responded both to faces and abstract patterns, and the majority of these neurons responded selectively to a particular associative pair. It was demonstrated that in addition to the view-invariant identity of faces used in the APA task, the population of AITv neurons was also able to represent the associative pairing between faces and abstract patterns, which was acquired by training in the APA task. It also appeared that the effect of associative pairing was not so strong that the abstract pattern could be treated in a manner similar to a series of faces belonging to a unique identity. Together, these findings indicate that the AITv plays a crucial role in both facial identification and semantic associations with facial identities.