Lactate dehydrogenase in hypothermia-treated newborn infants with hypoxic-ischaemic encephalopathy
Lactate dehydrogenase in hypothermia-treated newborn infants with hypoxic-ischaemic encephalopathy
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DOI：
10.1111/j.1651-2227.2012.02778.x
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发表时间：
2012-10-01
期刊：
影响因子：
3.8
通讯作者：
Karlsson, Mathias
中科院分区：
文献类型：
--
作者：
Thoresen, Marianne;Liu, Xun;Karlsson, Mathias
目的：我们研究血浆乳酸脱氢酶（LDH）是否能预测低温（HT）治疗的中重度缺氧缺血性脑病（HIE）足月婴儿的预后，以及LDH在有急性和非急性围产期损伤和产后崩溃（PNC）证据的婴儿之间是否存在差异。方法：回顾性分析39例经ht治疗的HIE患儿的资料。不良结果定义为18个月时的心理和/或精神运动发育指数（贝利婴儿发育量表II）
Aims: We investigated whether plasma lactate dehydrogenase (LDH) predicts outcome in hypothermia (HT)-treated term infants with moderate/severe hypoxic-ischaemic encephalopathy (HIE) and additionally whether LDH differs between infants with evidence for acute and nonacute perinatal insults and postnatal collapse (PNC). Methods: Data from HT-treated infants with HIE (n = 39) were analysed retrospectively. Adverse outcome was defined as a Mental and/or Psychomotor Developmental Index (Bayley Scales of Infant Development II), at 18 months