The financial costs of healthcare treatment for people with Type 1 or Type 2 diabetes in the UK with particular reference to differing severity of peripheral neuropathy
The financial costs of healthcare treatment for people with Type 1 or Type 2 diabetes in the UK with particular reference to differing severity of peripheral neuropathy
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DOI：
10.1111/j.1464-5491.2006.02057.x
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发表时间：
2007-02-01
影响因子：
3.5
通讯作者：
Peters, J. R.
中科院分区：
文献类型：
--
作者：
Currie, C. J.;Poole, C. D.;Peters, J. R.
目的描述糖尿病患者周围神经病变(DPN)的症状严重程度，并分析其与医疗资源使用的关系。一项邮寄调查被张贴在被确认为患有糖尿病的受试者身上。收集人口学、生活质量(EQ-5D和SF-36)和神经病症状(NTSS-6和QOL-DN)数据。这些数据被链接到编码到医疗资源组(HRGs)中的常规医疗数据，然后根据英国国家参考成本进行成本计算。结果共收到1298名患者的调查回复，回复率为32%。在临床确诊为糖尿病周围神经病变的患者中，NTSS-6-SA平均得分为6.16vs.3.19(P<；0.001)。糖尿病病程并不随神经病变症状的严重程度而改变，但平均糖化血红蛋白(1c)和体重指数随症状严重程度的增加而增加(分别为7.6%~8.1%，P=0.023；28.0~30.9 kg/m(2)，P<；0.001)。一般线性模型显示，NTSS-6-SA评分是年度卫生资源成本和年度处方药成本的显著预测因子。平均而言，NTSS-6-SA得分每增加1分，一级和二级医疗费用就会增加6%，转换成对数的药物费用就会增加3%。结论本研究表明，DPN症状的严重程度与医疗资源的使用增加有关，从而与费用有关。
Aims To characterize symptom severity of diabetic peripheral neuropathy (DPN) in people with diabetes and to characterize its association with healthcare resource use.Methods The study was undertaken in Cardiff and the Vale of Glamorgan, UK. A postal survey was posted to subjects identified as having diabetes. Demography, quality of life (EQ-5D and SF-36) and symptoms of neuropathy (NTSS-6 and QOL-DN) data were collected. These data were linked to routine healthcare data coded into healthcare resource groups (HRGs) and subsequently costed according to UK National reference costs.Results Survey responses were received from 1298 patients, a 32% response rate. For patients with a clinically confirmed diagnosis of DPN, the mean NTSS-6-SA score was 6.16 vs. 3.19 (P < 0.001). Duration of diabetes did not change across groups defined by severity of neuropathy symptoms, but mean HbA(1c) and body mass index values did increase with symptom severity (range 7.6-8.1%, P = 0.023; and 28.0-30.9 kg/m(2), P < 0.001, respectively). General linear modelling showed that the NTSS-6-SA score was a significant predictor of both annual health resource costs and yearly prescribed drug costs. On average, each 1-point increase in NTSS-6-SA score predicted a 6% increase in primary and secondary care costs and a 3% increase in log transformed drug costs.Conclusion This study demonstrated that severity of DPN symptoms was associated with increased healthcare resource use, thus costs.