Predictors of adherence and contamination in a randomized trial of exercise in colorectal cancer survivors

Predictors of adherence and contamination in a randomized trial of exercise in colorectal cancer survivors
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DOI:
10.1002/pon.802
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发表时间:
2004-12-01
期刊:
影响因子:
3.6
通讯作者:
Fairey, AS
Fairey, AS
中科院分区:
医学2区
文献类型:
--
作者:
Courneya, KS;Friedenreich, CM;Fairey, AS

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本研究的目的是在一项随机对照试验中,在结直肠癌幸存者中检查运动坚持性(即干预组的运动)和运动污染(即对照组的运动)的预测因素。在基线时,102名参与者完成了计划行为理论,个性,过去的运动,运动变化阶段,身体健康和医疗/人口统计学的测量,然后以2:1的比例随机分配到运动组(n = 69)或对照组(n = 33)。每周通过电话进行自我报告,持续16周。93例(91%)受试者完成了试验。运动组的依从性为76%,对照组的污染率为52%。分层逐步回归分析表明,基线运动阶段的变化(β = 0.35; p = 0.001),就业状况(β = -0.28; p = 0.010),治疗方案(beta = -0.26; p = 0.018)和知觉行为控制(beta = 0.20; p = 0.055)解释了锻炼坚持性的39.6%的方差。意图(β = 0.36; p = 0.049)和基线运动阶段的变化(β = 0.30:p = 0.095)解释了运动污染的29.9%的方差。这些发现可能对在结直肠癌幸存者中进行运动的临床试验以及在临床试验之外向结直肠癌幸存者推广运动具有意义。版权所有(C)2004约翰威利父子有限公司。
The purpose of this study was to examine predictors of exercise adherence (i.e. exercise in the intervention group) and exercise contamination (i.e. exercise in the control group) in a randomized controlled trial of home-based exercise in colorectal cancer survivors. At baseline, 102 participants completed measures of the theory of planned behavior, personality, past exercise, exercise stage of change, physical fitness, and medical/demographics and then were randomly assigned in a 2:1 ratio to an exercise (n = 69) or control (n = 33) group. Exercise was monitored weekly for 16 weeks using self-reports by telephone. Ninety-three (91 %) participants completed the trial. Adherence was 76% in the exercise group and contamination was 52% in the control group. Hierarchical stepwise regression analyses indicated that baseline exercise stage of change (beta = 0.35; p = 0.001), employment status (beta = -0.28; p = 0.010), treatment protocol (beta = -0.26; p = 0.018), and perceived behavioral control (beta = 0.20; p = 0.055) explained 39.6% of the variance in exercise adherence. Intentions (beta = 0.36; p = 0.049) and baseline exercise stage of change (beta = 0.30: p = 0.095) explained 29.9% of the variance in exercise contamination. These findings may have implications for conducting clinical trials of exercise in colorectal cancer survivors and for promoting exercise to colorectal cancer survivors outside of clinical trials. Copyright (C) 2004 John Wiley Sons, Ltd.