Breast cancer survival in South Asian women in England and Wales
Breast cancer survival in South Asian women in England and Wales
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DOI：
10.1136/jech.2004.030965
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发表时间：
2005-05-01
影响因子：
6.3
通讯作者：
Coleman, MP
中科院分区：
文献类型：
--
作者：
Farooq, S;Coleman, MP
研究目标：估计英格兰和威尔士的南亚人和非南亚人之间乳腺癌发病率和生存率的种族和社会经济差异，并为最大的少数民族南亚人的癌症生存监测提供基线。研究背景：1986-90 年间，英格兰和威尔士有 115 712 名女性被诊断患有首例原发性浸润性乳腺癌，随访至 1995 年。方法/设计：根据名称通过计算机算法来归属种族群体。发病率源自 1991 年人口普查各民族的人口分母。根据年龄、物质匮乏的五分位数和种族群体来估计一年和五年的相对生存率，并使用全国死亡率来估计预期生存率。 主要结果：南亚女性的年龄标准化发病率（每年每 10 万人中 40.5 人）比所有其他女性（每 10 万人中 57.4 人）低 29%。南亚女性五年龄标准化相对生存率为 70.3%（95% CI 65.2 至 75.4），其他女性为 66.7%（66.4 至 67.0）。对于两个种族群体来说，最富裕群体的女性生存率比最贫困群体的女性高出 8%-9%。然而，在每个贫困类别中，南亚女性的生存率比其他女性高 3%-8%。 结论：这项全国性研究证实，南亚女性的乳腺癌发病率明显低于英格兰和威尔士的其他女性。它还提供了一些证据，表明 1990 年之前被诊断出的南亚女性的乳腺癌生存率高于英格兰和威尔士的其他女性，无论是总体还是在各个剥夺类别中。
Study objectives: To estimate ethnic and socioeconomic differences in breast cancer incidence and survival between South Asians and non-South Asians in England and Wales, and to provide a baseline for surveillance of cancer survival in South Asians, the largest ethnic minority.Setting: 115 712 women diagnosed with first primary invasive breast cancer in England and Wales during 1986-90 and followed up to 1995.Methods/design: Ethnic group was ascribed by a computer algorithm on the basis of the name. Incidence rates were derived from 1991 census population denominators for each ethnic group. One and five year relative survival rates were estimated by age, quintile of material deprivation, and ethnic group, using national mortality rates to estimate expected survival.Main results: Age standardised incidence was 29% lower among South Asian women (40.5 per 100 000 per year) than among all other women (57.4 per 100 000). Five year age standardised relative survival was 70.3% (95% CI 65.2 to 75.4) for South Asian women and 66.7% (66.4 to 67.0) for other women. For both ethnic groups, survival was 8%-9% higher for women in the most affluent group than those in the most deprived group. In each deprivation category, however, survival was 3%-8% higher for South Asian women than other women.Conclusions: This national study confirms that breast cancer incidence is substantially lower in South Asians than other women in England and Wales. It also provides some evidence that South Asian women diagnosed up to 1990 had higher breast cancer survival than other women in England and Wales, both overall and in each category of deprivation.