Tuberculosis incidence and risk factors among patients living with HIV/AIDS in public health service institutions in Brasilia, Federal District

Tuberculosis incidence and risk factors among patients living with HIV/AIDS in public health service institutions in Brasilia, Federal District
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DOI:
10.1590/s0037-86822008000600001
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发表时间:
2008-12-01
影响因子:
2
通讯作者:
Romero, Gustavo Adolfo Sierra
Romero, Gustavo Adolfo Sierra
中科院分区:
医学4区
文献类型:
--
作者:
Lannoy, Leonor Henriette de;Cortez-Escalante, Juan José;Romero, Gustavo Adolfo Sierra

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为了估计结核病的发病率和危险因素,回顾性队列的281名艾滋病毒阳性的成年人,谁被告知艾滋病方案的巴西利亚卫生部在1998年的临床图表,在2003年进行了审查。所有患者在纳入队列时均未接受过抗逆转录病毒治疗。在研究开始时,29名患者被确定为患有结核病。在60个月的随访中,确定了13例结核病病例,发病密度率为1.24/100人年。基线CD 4 + T淋巴细胞计数的患者中结核病发病率最高
In order to estimate the incidence of and risk factors for developing tuberculosis, the clinical charts of a retrospective cohort of 281 HIV-positive adults, who were notified to the AIDS Program of the Health Department of Brasilia in 1998, were reviewed in 2003. All the patients were treatment-naive regarding antiretroviral therapy at the time of inclusion in the cohort. Twenty-nine patients were identified as having tuberculosis at the start of the study. Thirteen incident tuberculosis cases were identified during the 60 months of follow-up, with an incidence density rate of 1.24/100 person-years. Tuberculosis incidence was highest among patients with baseline CD4+ T-lymphocyte counts