Prevalence of Risk Factors for Metabolic Syndrome in Adolescents National Health and Nutrition Examination Survey (NHANES), 2001-2006
Prevalence of Risk Factors for Metabolic Syndrome in Adolescents National Health and Nutrition Examination Survey (NHANES), 2001-2006
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DOI：
10.1001/archpediatrics.2009.3
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发表时间：
2009-04-01
影响因子：
--
通讯作者：
Katzmarzyk, Peter T.
中科院分区：
文献类型：
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作者：
Johnson, William D.;Kroon, Jolanda J. M.;Katzmarzyk, Peter T.
目的：调查青少年代谢综合征不同组分组合的患病率。设计：一个复杂的、多阶段的、分层的地理区域设计，用于从非制度化的美国人口中收集代表性数据。设置：NHANES，由疾病控制和预防中心进行的国家健康持续监测。参与者：在2001-2002年、2003-2004年和2005-2006年NHANES数据发布中观察到的2400五十六例12至19岁的西班牙裔、白色和黑人青少年。代谢综合征定义为在以下测量中有3种或3种以上的疾病：腰围、血压、空腹甘油三酯、高密度脂蛋白血清胆固醇和葡萄糖。大约一半的参与者至少有一个紊乱的测量，总体代谢综合征患病率为8.6%（95%置信区间，6.5%-10.6%）。男性（10.8%）的患病率高于女性（6.1%），西班牙裔（11.2%）和白色（8.9%）的患病率高于黑人（4.0%）。在黑人女性中，腰围大的患病率很高（23.3%），但在黑人青少年中，没有代谢综合征的组成部分占主导地位。在西班牙裔和白色青少年中，腰围大、空腹甘油三酯高和高密度脂蛋白血清胆固醇低是显著因素;在西班牙裔和白色男性中，血糖浓度高是显著因素。黑人青少年中代谢综合征的低患病率，与代谢综合征患者中所有5种危险因素的一致低患病率平行，在心脏代谢紊乱早发的时间表中，这预示着种族差异。
Objective: To investigate the prevalence of distinct combinations of components of the metabolic syndrome among adolescents.Design: A complex, multistage, stratified geographic area design for collecting representative data from the non-institutionalized US population.Setting: The NHANES, an ongoing surveillance of the nation's health conducted by the Centers for Disease Control and Prevention.Participants: Two thousand four hundred fifty-six Hispanic, white, and black adolescents aged 12 to 19 years observed in the 2001-2002, 2003-2004, and 2005-2006 NHANES data releases.Main Outcome Measures: Metabolic syndrome was defined as having 3 or more disorders in the following measurements: waist circumference, blood pressure, fasting triglycerides, high-density lipoprotein serum cholesterol, and glucose.Results: About half of the participants had at least 1 disordered measurement, with an overall metabolic syndrome prevalence of 8.6% (95% confidence interval, 6.5%-10.6%). Prevalence was higher in males (10.8%) than females (6.1%), and in Hispanic (11.2%) and white (8.9%) individuals than in black individuals (4.0%). In black females, there was a high prevalence of a large waist circumference (23.3%), but no component of metabolic syndrome dominated its diagnosis in black adolescents of either sex. A large waist circumference and high fasting triglyceride and low high-density lipoprotein serum cholesterol concentrations were salient factors in Hispanic and white adolescents of both sexes; high glucose concentrations were prominent among Hispanic and white males.Conclusion: The low prevalence of metabolic syndrome in black adolescents, in parallel with uniformly low prevalence of all 5 risk factors among those with metabolic syndrome, portend ethnic disparities in the time table for early onset of cardiometabolic disorders.