Ruthenium-Catalyzed C-H Arylation of Diverse Aryl Carboxylic Acids with Aryl and Heteroaryl Halides.
Ruthenium-Catalyzed C-H Arylation of Diverse Aryl Carboxylic Acids with Aryl and Heteroaryl Halides.
复制标题
用芳基和杂芳基卤化物对各种芳基羧酸的芳族催化的C-H芳基化。
DOI：
10.1021/acs.orglett.6b02862
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发表时间：
2016-10-21
期刊：
影响因子：
5.2
通讯作者：
Weix DJ
中科院分区：
文献类型：
--
作者：
Huang L;Weix DJ
Ruthenium ligated to tricyclohexylphosphine or di-tert-butylbipyridine catalyzes the arylation of carboxylic acids with diverse aryl halides (iodide, bromide, and triflate; aryl and heteroaryl). In addition, arylations with 2-iodophenol formed benzochromenones, carboxylate was shown to be a stronger donor than an amide, and the arylation of a pyridine carboxylate was demonstrated. Stoichiometric studies demonstrated that the added ligand is required for reaction with the electrophile but not the C–H bond.
