Increased hippocampal volumes in adults with high functioning autism spectrum disorder and an IQ > 100: A manual morphometric study

Increased hippocampal volumes in adults with high functioning autism spectrum disorder and an IQ > 100: A manual morphometric study
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DOI:
10.1016/j.pscychresns.2015.08.002
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发表时间:
2015-10-30
影响因子:
2.3
通讯作者:
Riedel, Andreas
Riedel, Andreas
中科院分区:
医学4区
文献类型:
--
作者:
Maier, Simon;van Elst, Ludger Tebartz;Riedel, Andreas

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Previous studies concerning the volumes of the amygdala and the hippocampus in autism spectrum disorders (ASD) show inconsistent results. We acquired magnetic resonance images of 30 individuals with ASD and individually matched controls. All participants had an IQ > 100 to increase the likelihood of including non-syndromal forms of ASD. Manually defined amygdala volumes showed no significant group difference, while hippocampi were significantly enlarged in ASD. This finding is discussed with regard to the 'intense world hypothesis'. (C) 2015 Elsevier Ireland Ltd. All rights reserved.