Association Between Daily Time Spent in Sedentary Behavior and Duration of Hyperglycemia in Type 2 Diabetes.
Association Between Daily Time Spent in Sedentary Behavior and Duration of Hyperglycemia in Type 2 Diabetes.
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DOI：
10.1177/1099800415600065
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发表时间：
2016-03
影响因子：
2.5
通讯作者：
Quinn L
中科院分区：
文献类型：
--
作者：
Fritschi C;Park H;Richardson A;Park C;Collins EG;Mermelstein R;Riesche L;Quinn L
运动和久坐行为的影响有不同的生理反应，这还没有得到充分的解释。久坐行为的时间与2型糖尿病风险成人的葡萄糖耐受不良有关，但这些数据主要来自横断面研究，没有探讨糖尿病成人的这种关系。本研究的具体目的是检查诊断为2型糖尿病的成年人在3至5天内久坐不动的时间与血糖水平之间的关系。研究方法：使用从腕部加速度计和连续葡萄糖监测系统（CGMS）收集的连续和并发数据，我们进行了一项纵向描述性研究，涉及86例2型糖尿病患者。结果：久坐行为时间越长，高血糖时间越长（B = 0.12，p < 0.05）。结论：这些发现强调了久坐时间和高血糖时间之间的因果关系，通过我们使用客观、连续的数据收集方法，在多天内对久坐行为和血糖水平进行了识别（Actiwatch，CGMS）。对于2型糖尿病患者，这些发现为制定个性化干预措施提供了可能性，这些干预措施旨在通过减少久坐时间来减少高血糖症的时间。
The effects of exercise and sedentary behavior have different physiologic responses, which have yet to be fully explained. Time spent in sedentary behavior has been associated with glucose intolerance in adults at risk for type 2 diabetes, but these data come largely from cross-sectional studies and do not explore this relationship in adults with diabetes. The specific aim of this study was to examine the relationship between time spent in sedentary behavior and glucose levels in adults with diagnosed type 2 diabetes over 3 to 5 days. Methods: Using continuous and concurrent data gathered from wrist accelerometry and a continuous glucose monitoring system (CGMS), we conducted a longitudinal, descriptive study involving 86 patients with type 2 diabetes. Results: More time spent in sedentary behavior was predictive of significant increases in time spent in hyperglycemia (B = 0.12, p < 0.05). Conclusions: These findings highlight the entwined relationship between time spent sedentary and time spent in hyperglycemia identified through our use of objective, continuous data collection methods for both sedentary behavior and glucose levels across multiple days (Actiwatch, CGMS). For patients with type 2 diabetes, these findings offer possibilities for the development of individualized interventions aimed at decreasing the amount of time spent in hyperglycemia by reducing sedentary time.