Three-dimensional ultrasound features of the polycystic ovary and the effect of different phenotypic expressions on these parameters
Three-dimensional ultrasound features of the polycystic ovary and the effect of different phenotypic expressions on these parameters
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DOI：
10.1093/humrep/dem218
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发表时间：
2007-12-01
影响因子：
6.1
通讯作者：
Raine-Fenning, Nick J.
中科院分区：
文献类型：
--
作者：
Lam, Po M.;Johnson, Ian R.;Raine-Fenning, Nick J.
背景：本研究的目的是量化患有多囊卵巢综合征 (PCOS) 的白人女性卵巢的三维 (31)) 超声特征，并检查这些值在不同表型之间是否存在差异。方法：对 40 名 PCOS 女性和 40 名对照患者进行 3D 盆腔超声检查。使用31)功率多普勒和二维脉冲波多普勒测量总卵巢体积、基质体积和回声性以及窦卵泡计数(AFC)并量化卵巢血流量。结果：患有 PCOS 的女性具有较高的 AFC（每个卵巢中位数为 16.3 与 5.5，P < 0.001）和卵巢体积（12.56 与 5.66 ml，P < 0.001）。 PCOS 女性的基质体积（10.79 对比 4.69 毫升，P < 0.001）和基质血管化（VI：3.85 对比 2.79%，P < 0.001；VFI：1.27 对比 0.85，P < 0.001）也有所增加。患有 PCOS 的女性和对照组之间的基质回声或脉冲波多普勒指数没有显着差异。在 PCOS 女性中，30 名多毛女性的卵巢血管分布显着高于正常雄激素女性（FI：33.94 对比 29.30，P < 0.05），14 名体重正常的 PCOS 女性与肥胖女性相比（VI：4.51 % 对比 3.25 %，P < 0.05；VFI：1.56 对比 1.22， P<0.05）。结论：根据 3D 超声，患有 PCOS 的女性基质体积和血管分布增加。多毛且体重正常的多囊卵巢综合症女性的基质血管分布明显较高。
BACKGROUND: The aim of this study was to quantify the three-dimensional (31)) ultrasound characteristics of ovaries in Caucasian women with polycystic ovarian syndrome (PCOS) and to examine if these values differed between different phenotypic forms. METHODS: 3D pelvic ultrasound was performed in 40 women with PCOS and in 40 controls. Total ovarian volume, stromal volume and echogenicity and antral follicle count (AFC) were measured and ovarian blood flow was quantified using both 31) power Doppler and two-dimensional pulsed-wave Doppler. RESULTS: Women with PCOS had a higher AFC (median 16.3 versus 5.5 per ovary, P < 0.001) and ovarian volume (12.56 versus 5.66 ml, P < 0.001). Stromal volume (10.79 versus 4.69 ml, P < 0.001) and stromal vascularization (VI: 3.85 versus 2.79%, P < 0.001; VFI: 1.27 versus 0.85, P < 0.001) were also increased in women with PCOS. There were no significant differences in stromal echogenicity or pulsed-wave Doppler indices between women with PCOS and the controls. Among the women with PCOS, ovarian vascularity was significantly higher in 30 women who were hirsute compared with normoandrogenic women (FI: 33.94 versus 29.30, P < 0.05) and in 14 women with PCOS who were of normal weight compared with obese women (VI: 4.51 versus 3.25 %, P < 0.05; VFI: 1.56 versus 1.22, P < 0.05). CONCLUSIONS: Based on 3D ultrasound, women with PCOS have an increased stromal volume and vascularity. Stromal vascularity is significantly higher in women with PCOS who are hirsute and of normal weight.