Electrical Stimulation of the Human Descending Motor Tracts at Several Levels
Electrical Stimulation of the Human Descending Motor Tracts at Several Levels
复制标题
人体下降运动束的多层次电刺激
DOI：
10.1017/s0317167100040476
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
I. Kanazawa
中科院分区：
文献类型：
--
作者：
Y. Ugawa;K. Genba;I. Kanazawa
摘要：使用高压电刺激技术在四个水平激活下行运动束：运动皮质、脑干（在锥体交叉周围）以及第一和第六胸椎水平（T1、T6）。记录胫骨前肌或趾短伸肌的肌电活动。所有正常受试者均能诱发出一致的运动动作电位。下行束的传导速度估计为62至79 m/s。运动神经元的突触延迟和利用时间（脊髓延迟时间）的总和估计为0.5 ± 0.3 ms，表明单突触或寡突触连接。在弥漫性影响下行束的患者中，该技术显示下行束传导沿着减慢，脊髓延迟时间延长，可能包括兴奋性突触后电位的时间总和所需的时间以及突触延迟和利用时间。在局部病变的患者中，在适当的节段发现了局部传导延迟。
ABSTRACT: The descending motor tracts were activated using a high voltage electrical stimulation technique at four levels: the motor cortex, brainstem (around the pyramidal decussation), and the first and sixth thoracic vertebral levels (Tl, T6). Electromyographic activity was recorded from the tibialis anterior or extensor digitorum brevis muscles. Consistent motor action potentials could be evoked in all normal subjects. The conduction velocity of the descending tracts was estimated to be 62 to 79 m/s. The sum of synaptic delay and utilization time at the motoneurons (spinal delay time) was estimated to be 0.5 ± 0.3 ms indicating a mono- or oligosynaptic connection. In patients with diffusely affected descending tracts, the technique showed slowed conduction along the descending tracts and prolonged spinal delay time which may include the time required for temporal summation of excitatory postsynaptic potentials as well as synaptic delay and utilization time. In patients with a localized lesion, localized conduction delay was found at the appropriate segment.