Electrospinning and Electrospray for Biomedical Applications
Electrospinning and Electrospray for Biomedical Applications
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DOI：
10.1016/b978-0-12-801238-3.11028-1
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发表时间：
2019-01-01
期刊：
影响因子：
--
通讯作者：
Zhao, Qilong
中科院分区：
文献类型：
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作者：
Wang, Min;Zhao, Qilong
在过去的20年里，静电纺丝和电喷雾分别可以产生纳米纤维和纳米颗粒，在生物医学领域引起了广泛的关注。静电纺丝纳米纤维支架类似于人体组织的纳米纤维细胞外基质，并促进组织再生。电喷雾颗粒为药物、生长因子、基因等在人体内的受控释放提供了合适的递送载体。基于传统静电纺丝或电喷雾的先进技术可用于开发新的医疗器械。将静电纺丝和电喷雾相结合为制造新型多功能医疗器械提供了新的手段。本章涵盖了静电纺丝和静电喷雾的基本原理以及它们在生物医学领域的应用。给出的例子显示了用于构建各种医疗设备的电纺丝和电喷雾的简单性、多功能性和适应性。然而，尽管电纺丝和电喷雾在生物医学领域取得了成功，但要实现其在生物医学应用中的全部潜力，仍然需要解决许多挑战。
Over the past 20 years, electrospinning and electrospray, which can produce nanofibers and nanoparticles, respectively, have attracted much attention in the biomedical field. Electrospun nanofibrous scaffolds resemble the nanofibrous extracellular matrix of human body tissues and facilitate tissue regeneration. Electrosprayed particles provide suitable delivery vehicles for the controlled release of drugs, growth factors, genes, etc. in human bodies. Advanced techniques based on conventional electrospinning or electrospray can be used to develop new medical devices. Integrating electrospinning and electrospray provides new means for fabricating novel multifunctional medical devices. This chapter covers fundamentals of electrospinning and electrospray and also their applications in the biomedical field. Examples given show the simplicity, versatility, and adaptability of electrospinning and electrospray for constructing various medical devices. However, despite the success of electrospinning and electrospray in the biomedical field, there are still many challenges that need to be addressed for realizing their full potential for biomedical application.