Facilitation of implicit motor learning by weak transcranial direct current stimulation of the primary motor cortex in the human
Facilitation of implicit motor learning by weak transcranial direct current stimulation of the primary motor cortex in the human
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DOI：
10.1162/089892903321662994
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发表时间：
2003-05-15
影响因子：
3.2
通讯作者：
Tergau, F
中科院分区：
文献类型：
--
作者：
Nitsche, MA;Schauenburg, A;Tergau, F
经颅施加的微弱直流电能够调节人的运动皮质兴奋性。阳极刺激增强兴奋性，阴极刺激减弱兴奋性。大脑皮层兴奋性变化伴随着运动学习。在这里，我们证明了微弱的直流电能够改善人类的内隐运动学习。在一系列反应时间任务的执行过程中，初级运动皮质、运动前皮质或前额叶皮质被刺激到与执行任务的手相反的位置。对初级运动皮质的阳极刺激导致了操作能力的提高，而对其余皮质的刺激则没有任何效果。我们认为初级运动皮质参与了内隐运动学习的习得和早期巩固阶段。
Transcranially applied weak direct currents are capable of modulating motor cortical excitability in the human. Anodal stimulation enhances excitability, cathodal stimulation diminishes it. Cortical excitability changes accompany motor learning. Here we show that weak direct currents are capable of improving implicit motor learning in the human. During performance of a serial reaction time task, the primary motor cortex, premotor, or prefrontal cortices were stimulated contralaterally to the performing hand. Anodal stimulation of the primary motor cortex resulted in increased performance, whereas stimulation of the remaining cortices had no effect. We conclude that the primary motor cortex is involved in the acquisition and early consolidation phase of implicit motor learning.