UNINTENTIONAL WEIGHT-LOSS IN THE UNITED-STATES

UNINTENTIONAL WEIGHT-LOSS IN THE UNITED-STATES
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DOI:
10.1093/oxfordjournals.aje.a117557
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发表时间:
1995-11-15
影响因子:
5
通讯作者:
EVERHART, JE
EVERHART, JE
中科院分区:
医学2区
文献类型:
--
作者:
MELTZER, AA;EVERHART, JE

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较低的体重通常被认为有利于健康,但体重减轻与死亡率增加有关。对这一悖论的一个解释可能是,减肥的好处可能取决于减肥是有意的还是无意的。作者在美国人口的全国代表性样本中调查了有意和无意的体重减轻与已知的发病率和死亡率危险因素的关联是否有所不同,该样本由 9,144 名 45 岁及以上的人组成,他们回答了有关糖尿病危险因素 1 年体重变化的问题 1989 年全国健康访谈调查 (NHIS) 的当前健康主题,统计分析纳入了调查设计的样本权重和特征,相对于常见的在参考组中,与减肥相关的因素有所不同,具体取决于减肥是否被定义为有意减肥、无意减肥或与有意无关。限制对 1,999 名减肥者进行分析,相对于有意减肥,无意减肥与年龄较大、健康状况较差、吸烟、体重指数较低以及仅在男性中丧偶和教育程度较低显着相关(p < 0.05),因此,无意减肥可以作为一个标志对于那些比有意减肥的人具有更高死亡风险的因素,此外,减肥意向可能有助于澄清体重减轻和死亡率之间的关系,到目前为止,这种关系已显示出违反直觉的结果。对体重减轻和死亡率之间关系的研究应将意图作为分析中的一个因素。
Lower weight is usually considered advantageous to health, yet weight loss has been associated with increased mortality. An explanation for this paradox might be that the benefits of weight loss may depend on whether the loss is intentional or unintentional. The authors investigated whether intentional and unintentional weight loss differed in their associations with known risk factors for morbidity and mortality in a nationally representative sample of the US population, The sample consisted of 9,144 persons, aged 45 years and older, who answered questions regarding I-year weight change in the diabetes risk factor Current Health Topic of the 1989 National Health interview Survey (NHIS), Statistical analyses incorporated the sample weights and characteristics of the survey design, Relative to a common referent group, the factors associated with weight loss differed depending on whether the loss was defined as intentional loss, as unintentional loss, or regardless of intention, Restricting analysis to the 1,999 persons who lost weight, unintentional relative to intentional weight loss was significantly (p < 0.05) associated with older age, poorer health status, smoking, lower body mass index, and, in men only, widowhood and less education, Thus, unintentional weight loss may serve as a marker for factors that characterize persons at greater risk of mortality than persons undergoing intentional weight loss, Also, intention to lose weight may help clarify the relation between weight loss and mortality that, to this point, has shown counterintuitive results. Studies of the relation between weight loss and mortality should incorporate intention as a factor in the analysis.