Statics and dynamics of single DNA molecules confined in nanochannels
Statics and dynamics of single DNA molecules confined in nanochannels
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DOI：
10.1103/physrevlett.94.196101
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发表时间：
2005-05-20
影响因子：
8.6
通讯作者：
Austin, RH
中科院分区：
文献类型：
--
作者：
Reisner, W;Morton, KJ;Austin, RH
成功设计用于操纵生物聚合物的纳米流体装置需要了解软凝聚态物理学的预测如何与装置尺寸成比例。在这里，我们提出了测量的DNA在纳米通道中扩展，并表明，低于临界宽度约两倍的持久性长度有一个交叉的聚合物物理。
The successful design of nanofluidic devices for the manipulation of biopolymers requires an understanding of how the predictions of soft condensed matter physics scale with device dimensions. Here we present measurements of DNA extended in nanochannels and show that below a critical width roughly twice the persistence length there is a crossover in the polymer physics.