Hydroxylated polymethoxyflavones and methylated flavonoids in sweet orange (Citrus sinensis) peel
Hydroxylated polymethoxyflavones and methylated flavonoids in sweet orange (Citrus sinensis) peel
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DOI：
10.1021/jf060234n
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发表时间：
2006-06-14
影响因子：
6.1
通讯作者：
Ho, Chi-Tang
中科院分区：
文献类型：
--
作者：
Li, Shiming;Lo, Chih-Yu;Ho, Chi-Tang
柑橘属中的多甲氧基黄酮（PMFs）因其具有广泛的生物活性，包括抗炎、抗癌和抗动脉粥样硬化特性而备受关注。人们对探索柑橘类水果中PMFs对健康有益的特性越来越感兴趣。因此，从甜橙（Citrus sinensis）果皮中分离和鉴定PMFs将为橙汁加工的副产品以及其他橙子消费在营养保健品和药品中的新应用提供可能。在我们的研究中，从甜橙皮中分离出了8种羟基化多甲氧基黄酮、6种多甲氧基黄酮、1种多甲氧基黄烷酮、1种羟基化多甲氧基黄烷酮和2种羟基化多甲氧基查耳酮，并通过各种质谱、紫外和不同的核磁共振技术阐明了它们的结构。一些羟基化多甲氧基黄酮和查耳酮是首次从甜橙皮中分离出来的。
Polymethoxyflavones (PMFs) from citrus genus have been of particular interest because of their broad spectrum of biological activities, including antiinflammatory, anticarcinogenic, and antiatherogenic properties. There have been increasing interests in the exploration of health beneficial properties of PMFs in citrus fruits. Therefore, the isolation and characterization of PMFs from sweet orange (Citrus sinensis) peel will lead to new applications of the byproducts from orange juice processes and other orange consumption in nutraceutical and pharmaceutical products. In our study, eight hydroxylated PMFs, six PMFs, one polymethoxyflavanone, one hydroxylated polymethoxyflavanone, and two hydroxylated polymethoxychalcones were isolated from sweet orange peel and their structures were elucidated by various MS, UV, and different NMR techniques. Some of the hydroxylated PMFs and chalcones are newly isolated from sweet orange peel.