New Insights into Podocyte Biology in Glomerular Health and Disease

New Insights into Podocyte Biology in Glomerular Health and Disease
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DOI:
10.1681/asn.2017010027
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发表时间:
2017-06-01
影响因子:
13.6
通讯作者:
Huber, Tobias B.
Huber, Tobias B.
中科院分区:
医学1区
文献类型:
--
作者:
Assady, Suheir;Wanner, Nicola;Huber, Tobias B.

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足细胞和肾小球研究是发展慢性进展性肾脏疾病的预防和治疗策略的中心。第11届国际足细胞会议于2016年4月3日至6日在以色列海法和耶路撒冷举行,来自世界各地的与会者介绍了他们在足细胞研究方面的新进展。在这篇综述中,我们简要强调了在表征足细胞发育,代谢,获得性损伤和修复机制方面取得的进展,包括在确定遗传变异和microRNA的作用方面取得的进展,以及在诊断技术和治疗方面取得的进展。
Podocyte and glomerular research is center stage for the development of improved preventive and therapeutic strategies for chronic progressive kidney diseases. Held April 3-6, 2016, the 11th International Podocyte Conference took place in Haifa and Jerusalem, Israel, where participants from all over the world presented their work on new developments in podocyte research. In this review, we briefly highlight the advances made in characterizing the mechanisms involved in podocyte development, metabolism, acquired injury, and repair, including progress in determining the roles of genetic variants and microRNA in particular, as well as the advances made in diagnostic techniques and therapeutics.