Hybrid nanoparticles for magnetic resonance imaging of target-specific viral gene delivery
Hybrid nanoparticles for magnetic resonance imaging of target-specific viral gene delivery
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DOI：
10.1002/adma.200701952
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发表时间：
2007-10-19
影响因子：
29.4
通讯作者：
Cheon, Jinwoo
中科院分区：
文献类型：
--
作者：
Huh, Yong-Min;Lee, Eun-Sook;Cheon, Jinwoo
通过融合病毒和MnMEIO磁性纳米颗粒，开发了具有靶向感染、磁共振（MR）成像和基因递送的多功能能力的混合纳米颗粒。证明了它们在体外靶向特异性MR成像和增强的绿色荧光蛋白（eGFP）基因递送到CAR阳性细胞中的成功利用。
Hybrid nanoparticles with multi-functional capabilities of targeted infection, magnetic resonance (MR) imaging, and gene delivery are developed by fusing virus and MnMEIO magnetic nanoparticles. Their successful utilizations for in vitro target-specific MR imaging and enhanced green fluorescent protein (eGFP) gene delivery into CAR-positive cells are demonstrated.