The color of skin: yellow diseases of the skin, nails, and mucosa
The color of skin: yellow diseases of the skin, nails, and mucosa
复制标题
DOI：
10.1016/j.clindermatol.2019.07.019
复制
发表时间：
2019-09-01
影响因子：
2.7
通讯作者：
Logan, Richard A.
中科院分区：
文献类型：
--
作者：
Logan, Ian T.;Logan, Richard A.
从皮肤反射的颜色是皮肤病和全身疾病的重要指标。入射光受到皮肤中的发色团的吸收和散射。与黄光反射相关的发色团包括类胡萝卜素和胆红素。与这些和其他发色团相关的各种病理生理机制在检查时显示为黄色。本文从形态学角度对黄皮肤疾病的发病机制和临床特征进行综述。一个简短的总结，鉴别诊断，实验室调查和治疗提出。黄皮肤疾病是一个异质性群体，由角蛋白、弹性和结缔组织、脂质代谢和其他代谢、炎症或器官功能障碍状态的异常组成。患者会通过不同的途径出现，皮肤病可能先于全身性疾病，也可能紧随其后。皮肤科医生在识别那些恶性或系统性关联，以确保早期诊断和治疗至关重要的作用。爱思唯尔公司2019年版权所有版权所有。
The colors reflected from the skin are important indicators of dermatologic and systemic disorders. Incident light is subject to absorption by chromophores in the skin and scattering. Chromophores associated with yellow light reflection include the carotenoids and bilirubin. Various pathophysiologic mechanisms associated with these and other chromophores manifest with a yellow hue on examination. This review describes these mechanisms and the clinical features of yellow skin disorders by morphology. A brief summary of the differential diagnosis, laboratory investigations, and treatments are presented. Yellow skin disorders are a heterogenous group composed of abnormalities in keratin, elastic and connective tissue, lipid metabolism, and other states of metabolic, inflammatory, or organ dysfunction. Patients will present through different routes, and skin disease may precede or follow systemic disease. Dermatologists have an essential role in identifying those with malignant or systemic associations to ensure early diagnosis and treatment. Crown Copyright (C) 2019 Published by Elsevier Inc. All rights reserved.