O-nucleophilic amino alcohol acyl-transfer catalysts: the effect of acidity of the hydroxyl group on the activity of the catalyst.
O-nucleophilic amino alcohol acyl-transfer catalysts: the effect of acidity of the hydroxyl group on the activity of the catalyst.
复制标题
O-亲核氨基醇酰基转移催化剂：羟基的酸性对催化剂活性的影响。
DOI：
10.1021/ol035510n
复制
发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Sammakia,Tarek
中科院分区：
文献类型：
--
作者：
Wayman,KjirstenA;Sammakia,Tarek
氨基醇衍生的酰基转移催化剂以亲核机理起作用，羟基附近有吸电子基团的催化剂活性更强。这是由于催化剂羟基的酸度增加。
Amino alcohol-derived acyl-transfer catalysts are shown to operate by anO-nucleophilic mechanism, and catalysts bearing electron-withdrawing groups in proximity to the hydroxyl group are found to be more active. This is attributed to an increase in the acidity of the hydroxyl group of the catalyst.