Application of Underwater Shock Wave Focusing to the Development of Extracorporeal Shock Wave Lithotripsy
Application of Underwater Shock Wave Focusing to the Development of Extracorporeal Shock Wave Lithotripsy
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DOI：
10.1143/jjap.32.2192
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发表时间：
1993-05
影响因子：
1.5
通讯作者：
K. Takayama
中科院分区：
文献类型：
--
作者：
K. Takayama
本文介绍了东北大学冲击波研究中心与东北大学医学院密切合作开展的体外冲击波碎石（ESWL）发展研究项目的总结。ESWL是一种非侵入性临床治疗崩解的人类结石，也是冲击波最和平的应用之一。水下球形冲击波是由微炸药爆炸产生的。采用全息干涉流显示技术和聚偏氟乙烯（PVDF）压力传感器对水下激波和超声聚焦特性进行了研究。这些集中的压力，当应用于临床治疗时，可以有效和无创地瓦解尿路结石或胆囊结石。然而，尽管临床成功，但在ESWL治疗过程中会发生组织损伤，并简要描述了组织损伤的可能机制。
This paper describes a summary of a research project for the development of extracorporeal shock wave lithotripsy (ESWL), which has been carried out, under close collaboration between the Shock Wave Research Center of Tohoku University and the School of Medicine, Tohoku University. The ESWL is a noninvasive clinical treatment of disintegrating human calculi and one of the most peaceful applications of shock waves. Underwater spherical shock waves were generated by explosion of microexplosives. Characteristics of the underwater shock waves and of ultrasound focusing were studied by means of holographic interferometric flow visualization and polyvinyliden-difluoride (PVDF) pressure transducers. These focused pressures, when applied to clinical treatments, could effectively and noninvasively disintegrate urinary tract stones or gallbladder stones. However, despite clincal success, tissue damage occurs during ESWL treatments, and the possible mechanism of tissue damage is briefly described.