Synthesis, characterization, and biological application of size-controlled nanocrystalline NaYF4:Yb,Er infrared-to-visible up-conversion phosphors
Synthesis, characterization, and biological application of size-controlled nanocrystalline NaYF4:Yb,Er infrared-to-visible up-conversion phosphors
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DOI：
10.1021/nl048680h
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发表时间：
2004-11-01
期刊：
影响因子：
10.8
通讯作者：
Guo, LH
中科院分区：
文献类型：
--
作者：
Yi, GS;Lu, HC;Guo, LH
合成了纳米晶红外-可见光上转换发光材料--Yb和Er3+共掺的氟化钇钠盐。在乙二胺四乙酸(EDTA)存在下，采用共沉淀法制备了粒径分布较窄的球形粒子。通过调节EDTA与总镧系元素的摩尔比，得到了粒径在37~166 nm之间的可控颗粒。尽管所制备的纳米粒子在红外光激发下发出非常微弱的上转换荧光，但在400至600摄氏度的温度下热处理后，发射增强了40倍。通过与块体荧光粉的比较，估计该纳米颗粒的发光效率为1%。用多种显微和光谱技术研究了影响纳米粒子大小及其上转换荧光强度的因素。初步结果表明，纳米颗粒在检测生物相互作用方面具有很好的上转换荧光标记的前景。
Nanocrystalline infrared-to-visible up-conversion phosphors, ytterbium and erbium co-doped sodium yttrium fluoride, were synthesized. Spherical particles with narrow size distribution were prepared by a co-precipitation method in the presence of ethylenediaminetetraacetic acid (EDTA). Particles of controlled size in the range of 37 to 166 nm diameter were obtained by adjusting the molar ratio of EDTA to total lanthanides. Although the as-prepared nanoparticles emit very weak up-conversion fluorescence when excited by infrared light, the emission was enhanced by up to 40-fold after they were annealed at temperatures between 400 and 600 degreesC. By comparison with the bulk phosphor, the luminescence efficiency of the nanoparticle was estimated to be 1%. Factors affecting the particle size and their up-conversion fluorescence intensity were investigated by various microscopic and spectroscopic techniques. Preliminary results demonstrated the nanoparticles as promising up-converting fluorescence labels in the detection of biological interactions.