Pleural cavity angiosarcoma arising in chronic expanding hematoma after pneumonectomy
Pleural cavity angiosarcoma arising in chronic expanding hematoma after pneumonectomy
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DOI：
10.1016/j.humpath.2010.06.019
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发表时间：
2011-10-01
期刊：
影响因子：
3.3
通讯作者：
Fukayama, Masashi
中科院分区：
文献类型：
--
作者：
Miyazaki, Hideki;Goto, Akiteru;Fukayama, Masashi
一位52岁男性因肺鳞状细胞癌接受左肺切除术，术后无复发迹象。在68岁时，左侧胸膜腔出现一个包裹性巨大肿块，诊断为慢性扩张性血肿。发现后2年8个月，病变开始侵犯胸壁，10个月后，患者死于活动性出血和病变直接压迫心脏。尸检时，左胸腔被囊性出血性肿块占据，浸润到周围结构中。此外，在右肺中观察到散在的肿瘤结节。在组织学上，血管肉瘤的不规则坏死的血管内衬不典型的内皮细胞在慢性扩大的血肿。最后诊断为慢性扩张性血肿引起的胸膜腔血管肉瘤及其转移到右肺。(C)2011 Elsevier Inc. All rights reserved.
A 52-year-old man received a left pneumonectomy for pulmonary squamous cell carcinoma without signs of recurrence after surgery. At age 68 years, a capsulated huge mass developed in the left pleural cavity, which was diagnosed as chronic expanding hematoma. Two years and 8 months after detection, the lesion began to invade the chest wall, and 10 months later, the patient died of active bleeding and direct compression of the heart by the lesion. At autopsy, the left thoracic cavity was occupied by a cystic and hemorrhagic mass infiltrating into the surrounding structures. In addition, scattered tumorous nodules were observed in the right lung. Histologically, angiosarcoma with irregularly anastomosing vessels lined with atypical endothelial cells was noted in the chronic expanding hematoma. The final diagnosis was pleural cavity angiosarcoma arising in chronic expanding hematoma and its metastases to the right lung. (C) 2011 Elsevier Inc. All rights reserved.