Perinatal morbidity after in vitro fertilization is lower with frozen embryo transfer.
Perinatal morbidity after in vitro fertilization is lower with frozen embryo transfer.
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DOI：
10.1016/j.fertnstert.2010.05.049
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发表时间：
2011-03
影响因子：
6.7
通讯作者：
Barnhart KT
中科院分区：
文献类型：
--
作者：
Kansal Kalra S;Ratcliffe SJ;Milman L;Gracia CR;Coutifaris C;Barnhart KT
To study the association of perinatal outcome and IVF transfer type in a group of infertility patients with standardized treatment and similar prognosis. Retrospective cohort study. University-based infertility center, January 1998 to June 2006. Two hundred eighteen IVF pregnancies after fresh embryo transfer (ET); 122 IVF pregnancies after frozen ET. Assessment of perinatal outcome in fresh versus frozen ET pregnancies. Pregnancy outcomes after fresh versus frozen embryo transfer (ET). Primary outcome was a composite of three events: preterm delivery, intrauterine growth restriction, or low birth weight. Secondary outcomes were subtypes of pregnancy loss. Associations were assessed using multivariate logistic regression. The final sample included 340 pregnancies: 218 fresh and 122 frozen ETs. Singleton pregnancy was less likely after transfer of fresh embryos (odds ratio [OR] 0.39, 95% confidence interval [CI] 0.23–0.67), and pregnancies after fresh ET were more likely to end in first-trimester loss (OR 1.82, 95% CI 1.05–3.13). Composite adverse outcome after transfer of fresh (44.0%) versus frozen (32.6%) embryos was higher (OR 1.52, 95% CI 0.90–2.56) and was strongly associated with twin gestation (OR 23.82, 95% CI 11.16–50.82). Perinatal morbidity is higher in IVF pregnancies conceived after a fresh ET compared with a frozen ET. Although some differences are related to conception with twin gestations, these findings suggest that adverse outcomes may be related to differences in IVF procedures.
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影响因子：
7.2
作者：
Jackson, RA;Gibson, KA;Croughan, MS
通讯作者：
Croughan, MS
影响因子：
6.1
作者：
Ericson, A;Källén, B
通讯作者：
Källén, B
DOI：
10.1016/s0197-2456(97)00005-6
发表时间：
1997-12-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
Cannon, CP
通讯作者：
Cannon, CP
影响因子：
6.7
作者：
Chung, Karine;Coutifaris, Christos;Barnhart, Kurt T.
通讯作者：
Barnhart, Kurt T.
影响因子：
158.5
作者：
Schieve, LA;Meikle, SF;Wilcox, LS
通讯作者：
Wilcox, LS