Mono- and polynuclear copper(II) complexes based on 2,4,6-tris(2-pyridyl)-1,3,5-triazine and its hydrolyzed form
Mono- and polynuclear copper(II) complexes based on 2,4,6-tris(2-pyridyl)-1,3,5-triazine and its hydrolyzed form
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DOI：
10.1016/j.ica.2014.03.021
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发表时间：
2014-05-24
影响因子：
2.8
通讯作者：
Rudbari, Hadi Amiri
中科院分区：
文献类型：
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作者：
Abdi, Khatereh;Hadadzadeh, Hassan;Rudbari, Hadi Amiri
合成了三种五坐标Cu(II), [Cu(tptz)Cl-2]中心点2H(2)O (1), [Cu(bpca)Cl](n)(2)和[Cu(tptz)(dppz)](PF6)(2)(3)（3)(3)）配合物（tptz = 2,4,6-三（2-吡啶基）-1,3,5-三嗪，bpca =双（2-吡啶基羰基）酰胺阴离子，dppz =双吡啶[3,2-a:2 ',3 '-c]非那嗪）。在配合物1的水溶液中，通过铜（II）辅助水解tptz配体制备配合物2。配合物1和2的固体结构已用单晶x射线晶体学测定。配合物1含有离散的中性[Cu(tptz)Cl-2]基团，而配合物2则表现为通过氯配体连接的[Cu(bpca)Cl]单元的聚合链排列。在这两种配合物中，铜（II）中心周围的CuN3Cl2配位多面体最好地被描述为近方锥体，这是由三角指数tau值为0.12和0.02确定的。利用电子吸收、竞争荧光滴定、圆二色性和流动线性二色性研究了配合物3（作为其硝酸盐）与小牛胸腺DNA （CT-DNA）的相互作用。结果支持该复合物通过插层模式与CT-DNA的强结合亲和力。(C) 2014 Elsevier B.V.版权所有
Three complexes with five-coordinate Cu(II), [Cu(tptz)Cl-2]center dot 2H(2)O (1), [Cu(bpca)Cl](n) (2) and [Cu(tptz)(dppz)](PF6)(2) (3) (tptz = 2,4,6-tris(2-pyridyl)-1,3,5-triazine, bpca = bis(2-pyridylcarbonyl) amidate anion, and dppz = dipyrido[3,2-a:2 ',3 '-c]phenazine) have been synthesized and characterized. Complex 2 was prepared from an aqueous solution of complex 1 via copper(II)-assisted hydrolysis of the tptz ligand. The solid state structures of complexes 1 and 2 have been determined by single-crystal X-ray crystallography. Complex 1 contains discrete neutral [Cu(tptz)Cl-2] moieties, whereas complex 2 exhibits a polymeric chain arrangement built up of [Cu(bpca)Cl] units linked through the chloro ligands. In both complexes, the CuN3Cl2 coordination polyhedra around the copper(II) centers are best described as nearly square-pyramidal, as ascertained by trigonality index tau value of 0.12 for 1 and 0.02 for 2. The interaction between complex 3 (as its nitrate salt) and calf thymus DNA (CT-DNA) has been investigated by electronic absorption, competitive fluorescence titration, circular dichroism, and flow linear dichroism. The results support the strong binding affinity of the complex to CT-DNA via an intercalative mode. (C) 2014 Elsevier B.V. All rights reserved.