Reading abilities and cognitive functions of children with epilepsy:: Influence of epileptic syndrome
Reading abilities and cognitive functions of children with epilepsy:: Influence of epileptic syndrome
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DOI：
10.1016/j.braindev.2005.06.004
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发表时间：
2006-03-01
影响因子：
1.7
通讯作者：
Villeneuve, N
中科院分区：
文献类型：
--
作者：
Chaix, Y;Laguitton, V;Villeneuve, N
患有癫痫的儿童有出现学习障碍的风险。为了探讨癫痫综合征对阅读能力的影响，我们比较了 12 名良性特发性癫痫伴罗兰棘波儿童、10 名颞叶癫痫儿童和 12 名特发性全身性癫痫儿童的神经心理学特征。孩子们接受了一系列标准化测试，旨在评估：口语、阅读、短期记忆、注意力和行为调整。根据每组癫痫综合征的发病年龄、综合征持续时间和表现智商对方差分析进行调整。颞叶癫痫（TLE）儿童的阅读速度和理解能力得分显着较低，但癫痫变量（癫痫发作年龄、癫痫持续时间和癫痫活动度）影响了学业表现。在 TLE 组中，癫痫病灶的地形（左侧 TLE 与右侧 TLE）对阅读轮廓有明显影响。此外，癫痫综合征对 TLE 组的语音、语义和语言工作记忆缺陷也有影响。在较小程度上，患有特发性全身性癫痫（IGE）的儿童也表现出认知缺陷。本研究的结果支持了儿童癫痫特有的神经心理功能障碍模式，应考虑改善这些人群学业成绩不佳的补救措施。 (c) 2005 年 Elsevier B.V. 出版
Children with epilepsy are at risk of developing learning disorders. To explore the influence of the epileptic syndrome on reading abilities, we have compared the neuropsychological profile of 12 children with benign idiopathic epilepsy with rolandic spikes, 10 with temporal lobe epilepsy and 12 with idiopathic generalized epilepsy. Children underwent a selection of standardised tests designed to assess: oral language, reading, short-term memory, attention and behavioural adjustment. Analysis of variance was adjusted according to age of onset of the epileptic syndrome, duration of the syndrome, and performance IQ for each group. Children with temporal lobe epilepsy (TLE) had significantly lower scores for reading speed and comprehension, but epileptic variables (the age of onset of epilepsy, duration and activity of epilepsy) had influenced academic performances. In the TLE group there was a clear effect of the topography of the epileptic foci (left-side TLE vs. right-side TLE) on reading profile. Furthermore, the effect of epileptic syndromes was found in phonological, semantic and verbal working memory deficits in the TLE group. To a lesser extent children with idiopathic generalized epilepsy (IGE) also exhibit cognitive deficit. The results of the present study lend support to epilepsy-specific patterns of neuropsychological dysfunction in children that should be considered to improve remediation of academic underachievement in these populations. (c) 2005 Published by Elsevier B.V.