INCREASED PROTEIN-SYNTHESIS BY HUMAN PLATELETS DURING PHAGOCYTOSIS OF LATEX-PARTICLES INVITRO
INCREASED PROTEIN-SYNTHESIS BY HUMAN PLATELETS DURING PHAGOCYTOSIS OF LATEX-PARTICLES INVITRO
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DOI：
10.1055/s-0038-1647928
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发表时间：
1976-01-01
影响因子：
6.7
通讯作者：
DJALDETTI, M
中科院分区：
文献类型：
--
作者：
BESSLER, H;AGAM, G;DJALDETTI, M
A 3-fold increase of protein synthesis by human platelets during in vitro phagocytosis of polystyrene latex particles was detected. During the 1st 2 h of incubation, the percentage of phagocytizing platelets and the number of latex particles per platelet increased; by the end of the 3rd h, the 1st parameter remained stable while the number of latex particles per cell had decreased. Vincristine (20 .mu.g/ml of cell suspension) inhibited platelet protein synthesis. This effect was both time- and dose-dependent. The drug also caused a decrease in the number of phagocytizing cells, as well as in their phagocytotic activity.
