Preliminary report: hepatic fat and inflammation in type 2 diabetes mellitus.
Preliminary report: hepatic fat and inflammation in type 2 diabetes mellitus.
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DOI：
10.1016/j.metabol.2009.07.041
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发表时间：
2010-03
期刊：
影响因子：
--
通讯作者：
VADT
中科院分区：
文献类型：
--
作者：
Saremi A;Allison M;Ditomasso D;Ge L;Anderson R;Moritz TE;Duckworth W;Abraira C;Reaven PD;VADT
Although the association between inflammation and hepatic fat is fairly established, it remains unclear whether this association is independent of general measures of obesity and standard cardiovascular risk factors. Therefore, the aim of this study was to investigate the contribution of hepatic steatosis (HS) as an independent predictor of chronic inflammation in 281 subjects with type 2 diabetes. Hepatic steatosis significantly (p < 0.01) correlated with CRP (r= −0.16) and adiponectin (r=0.23). The association of HS with both CRP and adiponectin remained significant after adjustment for age, ethnicity, BMI (or WC), triglycerides, HDL, and total cholesterol. These data support the concept that accumulation of hepatic fat is related to enhanced inflammation in type 2 diabetes, independent of general measures of obesity and standard cardiovascular risk factors.
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影响因子：
158.5
作者：
Duckworth, William;Abraira, Carlos;Huang, Grant D.
通讯作者：
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影响因子：
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作者：
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DOI：
10.1152/ajpgi.00074.2008
发表时间：
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