aYChr-DB: a database of ancient human Y haplogroups.
aYChr-DB: a database of ancient human Y haplogroups.
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DOI：
10.1093/nargab/lqaa081
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发表时间：
2020-12
影响因子：
4.6
通讯作者：
Elhaik E
中科院分区：
文献类型：
--
作者：
Freeman L;Brimacombe CS;Elhaik E
古代y染色体DNA是确定时间和辨别数千年前发生的迁徙路线和人口过程起源的宝贵工具。在古基因组学采用高通量测序和捕获富集方法的推动下，在过去三年（2018-2020年），已发表的古代基因组数量几乎翻了两番。而古代mtDNA单倍群资源库是可用的，没有类似的资源存在于古代y染色体单倍群。在这里，我们提出了ayhr - db -一个从公元前41430年到公元1945年的1797个古代欧亚人类y染色体单倍群的综合收集。我们包括年龄、地点、基因组覆盖范围和相关考古文化的描述符。我们还制作了古代Y单倍群随时间分布的可视化图。ayhr - db数据库是种群基因组和古基因组研究的宝贵资源。
Ancient Y-Chromosomal DNA is an invaluable tool for dating and discerning the origins of migration routes and demographic processes that occurred thousands of years ago. Driven by the adoption of high-throughput sequencing and capture enrichment methods in paleogenomics, the number of published ancient genomes has nearly quadrupled within the last three years (2018–2020). Whereas ancient mtDNA haplogroup repositories are available, no similar resource exists for ancient Y-Chromosomal haplogroups. Here, we present aYChr-DB—a comprehensive collection of 1797 ancient Eurasian human Y-Chromosome haplogroups ranging from 44 930 BC to 1945 AD. We include descriptors of age, location, genomic coverage and associated archaeological cultures. We also produced a visualization of ancient Y haplogroup distribution over time. The aYChr-DB database is a valuable resource for population genomic and paleogenomic studies.