Exposure to indoor combustion and adult asthma outcomes: environmental tobacco smoke, gas stoves, and woodsmoke
Exposure to indoor combustion and adult asthma outcomes: environmental tobacco smoke, gas stoves, and woodsmoke
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DOI：
10.1136/thorax.57.11.973
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发表时间：
2002-11-01
期刊：
影响因子：
10
通讯作者：
Blanc, PD
中科院分区：
文献类型：
--
作者：
Eisner, MD;Yelin, EH;Blanc, PD
背景：由于患有慢性气道炎症，成年哮喘患者可能特别容易受到室内空气污染的影响。尽管广泛暴露于环境烟草烟雾（ETS），煤气炉，和woodsmoke，这些暴露对成人asthma的影响还没有得到很好的characterized.Methods：数据来自一项前瞻性队列研究的349名成人哮喘谁接受了结构化的电话采访，在基线和18个月的随访。ETS，煤气炉，和woodsmoke暴露对健康outcomes.Results的前瞻性影响：ETS暴露在基线访谈与受损的健康状况在纵向随访。与基线时没有自我报告暴露于ETS的受访者相比，较高水平的暴露（大于或等于7小时/周）与随访UP时哮喘严重程度评分较差相关，控制基线哮喘严重程度、年龄、性别、种族、收入和教育程度（平均评分增加1.5分; 95% CI 0.4 - 2.6）。在纵向随访中，较高水平的基线暴露于ETS也与较差的身体健康状况（平均下降-4.9分; 95% CI-8.4至-1.3）和哮喘特异性生活质量（平均增加4.4分; 95% CI-0.2至9.0）相关。较高水平的基线ETS暴露与急诊就诊（OR 3.4; 95% CI 1.1 - 10.3）和前瞻性随访时因哮喘住院的风险较高（OR 12.2; 95% CI 1.5 - 102）相关。煤气炉使用或woodstove暴露和哮喘的健康outcomes.Conclusion之间没有明确的关系：虽然煤气炉和woodstove暴露不会出现负面影响成人哮喘，ETS与健康状况的明显损害。
Background: Because they have chronic airway inflammation, adults with asthma may be particularly susceptible to indoor air pollution. Despite widespread exposure to environmental tobacco smoke (ETS), gas stoves, and woodsmoke, the impact of these exposures on adult asthma has not been well characterised.Methods: Data were used from a prospective cohort study of 349 adults with asthma who underwent structured telephone interviews at baseline and 18 month follow up. The prospective impact of ETS, gas stove, and woodsmoke exposure on health outcomes was examined.Results: ETS exposure at baseline interview was associated with impaired health status at longitudinal follow up. Compared with respondents with no baseline self-reported exposure to ETS, higher level exposure (greater than or equal to7 hours/week) was associated with worse severity of asthma scores at follow UP, controlling for baseline asthma severity, age, sex, race, income, and educational attainment (mean score increment 1.5 points; 95% Cl 0.4 to 2.6). Higher level baseline exposure to ETS was also related to poorer physical health status (mean decrement -4.9 points; 95% Cl -8.4 to -1.3) and asthma specific quality of life (mean increase 4.4 points; 95% Cl -0.2 to 9.0) at longitudinal follow up. Higher level baseline ETS exposure was associated with a greater risk of emergency department visits (OR 3.4; 95% Cl 1.1 to 10.3) and hospital admissions for asthma at prospective follow up (OR 12.2; 95% Cl 1.5 to 102). There was no clear relationship between gas stove use or woodstove exposure and asthma health outcomes.Conclusion: Although gas stove and woodstove exposure do not appear negatively to affect adults with asthma, ETS is associated with a clear impairment in health status.