Advances in transition metal (Pd, Ni, Fe)-catalyzed cross-coupling reactions using alkyl-organometallics as reaction partners.
Advances in transition metal (Pd, Ni, Fe)-catalyzed cross-coupling reactions using alkyl-organometallics as reaction partners.
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DOI：
10.1021/cr100327p
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发表时间：
2011-03-09
期刊：
影响因子：
62.1
通讯作者：
Sigman, Matthew S.
中科院分区：
文献类型：
--
作者：
Jana, Ranjan;Pathak, Tejas P.;Sigman, Matthew S.
过渡金属催化的有机亲电试剂和有机金属试剂的交叉偶联反应已经成为一种非常强大的合成工具，并且发展已经达到了允许广泛的偶联伙伴有效结合的复杂水平。1-3在过去的30年里，这种碳-碳键构建的范式使化学家能够组装具有多种兴趣的复杂分子框架，包括天然产物的全合成，药物化学和工业过程开发以及化学生物学，材料和纳米技术。交叉偶联作为一种流行的合成方法的出现源于这些反应中使用的有机金属试剂的多样性和可以掺入这些试剂中的广泛的官能团。4-11自从这篇评论最初提交以来，这类反应的重要性得到了诺贝尔化学奖的认可，理查德·赫克，根岸英一，
Transition metal-catalyzed cross-coupling reactions of organic electrophiles and organometallic reagents have emerged as a tremendously powerful synthetic tool, and the development has reached a level of sophistication that allows for a wide range of coupling partners to be combined efficiently. 1-3 In the past 3 decades, this paradigm for carbon-carbon bond construction has allowed chemists to assemble complex molecular frameworks of diversified interests encompassing total synthesis of natural products, medicinal chemistry, and industrial process development as well as chemical biology, materials, and nanotechnology. The emergence of cross-coupling as a popular method in synthesis arises from both the diversity of organometallic reagents utilized in these reactions and the broad range of functional groups which can be incorporated into these reagents. 4-11 Since initial submission of this review, the importance of this general class of reactions was recognized by the awarding of the Nobel prize in chemistry to Richard Heck, Ei-ichi Negishi, and
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影响因子：
5.2
作者：
Bhayana B;Fors BP;Buchwald SL
通讯作者：
Buchwald SL
影响因子：
2.8
作者：
Archambaud, Sylvie;Legrand, Frederic;Evain, M.
通讯作者：
Evain, M.
影响因子：
1.8
作者：
Bellina, F;Anselmi, C;Rossi, R
通讯作者：
Rossi, R
影响因子：
2.6
作者：
Barbero, Margherita;Cadamuro, Silvano;Dughera, Stefano
通讯作者：
Dughera, Stefano
影响因子：
3.6
作者：
Bach, T;Heuser, S
通讯作者：
Heuser, S